MONOGRAPH ABOUT GREEN SAP, NATURAL MEDICAMENT BASED ON THE
Dr. Bernardo Udaquiola
(Oncologist, Ex Coordinator Chief of Semiology and current Chief of Auto valid Department from the National Institute of Oncology of Uruguay, member of the expert group in introducing tunnel central venous catheters for chemotherapy and fluid perfusion)
Edited in March, 2003.
Dr. BERNARDO UDAQUIOLA´S CURRICULUM
DESCRIPTION OF GREEN SAP COMPONENTS.
MEDICAMENT´S USES AND TYPE OF ACTION.
Malignant prostate pathology: Mr. Eber Paiva
Malignant prostate pathology: Mr. Héctor Tanco.
Malignant prostate pathology: Mr. Raúl Smith.
Glandular hyperplasia with atypical focuses with
PIN III: Mr. Luis Mohana.
Malignant prostate pathology: Mr. Pablo Cordero.
Conclusions on anti-tumor GREEN SAP action on
malignant prostate neoplasies.
Light cell kidney adenocarcinoma pathology with
metastasis: Mr. Jorge Lindh
Pathology: Light cell adenocarcinoma and
hypernefroma: Mr. Jorge Suárez.
Kidney cancer: Mrs. Irma Renoldi
Pathology:
Wilms’ tumor: María Tabares
Conclusions on GREEN SAP action on Kidney
Neoplasies.
Malignant Ependimoma Pathology: E. Benegas
Malignant Ependimoma Pathology: Mauricio Ruiz.
Oligodendroglioma-glioblastoma Pathology: Sirvart
Doganian.
General conclusions on the GREEN SAP anti-tumor
action in the Central Nervous System.
Rectum cancer: Mr. Luis Peralta
Conclusions on GREEN SAP action on malignant
neoplasies of colon and rectum.
Lung Cancer with Brain Metastasis: Mrs. Liliana
Calzada
Lung epydermoid cancer: Mr. Honorio Pereira.
Conclusions on GREEN SAP Action on Lung-Bronchium
Carcinomas and its Metastasis.
Pancreatic cancer: Mrs. Herminia Andarnello
Conclusions on GREEN SAP Action on Pancreatic
tumours
Thyroid Cancer: Mrs. María Pilani
Conclusions on GREEN SAP Action on Thyroid
tumours.
Vulva-vaginal Carcinoma with Metastasis
Conclusions on GREEN SAP Action on vulva-vaginal
neoplasms.
Conclusions on GREEN SAP Action on skin neoplasms.
Some E-Mails received from patients treated with GREEN
SAP
HYGIENIC-DIETETIC RECOMMENDATIONS - Special for
patients being treated with GREEN SAP:
NCP: 55497
·
Medicine
doctor withdrawn from the University of the
·
Oncology
postgraduate from
·
Oncologist
doctor from the Oncology National Institute from January, 1994 until present.
·
Doctor
of Preventive Policlinics of the Oncology National Institute from 1994 until
present.
·
Collaborator
doctor of the Breast Cancer National Program from 1992 until present.
·
Retainer
doctor (hospitalization floor, radio, policlinics, emergency and Special Care
Unit) in
·
Substitute
doctor in
·
Oncologist
doctor in National Civil Employees Association, afterwards COMAEC, from 1994 to
2001.
·
Interviewer
doctor in the World Health Organization (1992)
·
Doctor
with largest casuistic in the last 5 years in the PRONACAM (National Program
against Breast Cancer)
·
Scientific
search on GREEN SAP drops action in the treatment of malignant neoplasies, from
April, 2000.
PUBLISHED SCIENTIFIC RESEARCHES.
Abroad
clerkships.
Congresses
and symposiums participation.
GREEN SAP medicament is 100% natural, elaborated in base of 3 herbs, BACCHARIS ARTICULATA, PLANTAGO
MAJOR, ROSMARINUS OFFICINALIS, without side effects and medicaments
interactions so it can be administered together with allopathic and/or
homeopathic treatments.
As a
Oncologist I was interested in searching any natural therapeutic that could
help my patients to pass this awful experience that is to have cancer.
In spite my
allopathic formation my conduct is to treat not to private the oncological
patient any therapeutic resource, just be traditional or product of alternative
medicine.
I dedicated
myself to search in nation and interantional bibliography and pharmacopeas
about medicinal plants that have antitumoral, antioxidatives and
inmunemodulator properties, to develop a product, wiht natural origin, non
agresive, to treat the cancer searching improve the quality of life of
oncological patient, knowing that not only must attack the tumor but only must
contemplate the patient.
So I conformed
a multidisciplinary team integrated by profesionals of differents areas between
them we find veterinarians, Pharmaceutical Chemist, Agronomus Engineer,
Biochemical Licenciated and Biology, as others investigators of different
countries so as to joint efforce to follow this objective.
It starts so the selection of herbs’s stage, choising
the ones that have tumoral action. According to its formulation this one has
caracteristics of an homeopathic complex, in relation to Schwabe’s pharmacopea.
The active principles act from the interior of the
organism, having in some opportunities local action when it’s necessary.
It’s of easy absorption, being its molecules integrables
to huma plasma quickly which is one of the elements that give its therapeutic
versality and its action’s perfile, following differents phases that improves
the delicate human homeostatic system to obtain the excellency of its action in
differents diseases and also the optimisation of health till to recover previous levels of it or directly
improve it; to levels that the body in this case ill didn’t get in, reaching it
by the administration of this product so natural as the soil where developpe
its components.
HERBS’S PROPERTIES THAT
COMPOSE GREEN SAP:
BACCHARIS ARTICULATA
Baccharis Articulata (Carqueja) has antioxidative
property (1), antiviral propertyl (2), antiulcerative property (3), hepatoprotective
and colague property (4), as cytotoxic (5) (6) (7)(8) and antimicrobial (9).
ROSMARINUS OFFICINALIS
Rosmarinus Officinalis (Romero) has also
antiproliferative activity (10) (11) (12)
PLANTAGO
MAJOR
Plantago Major has cytotoxic and inmunomodulative activity (13) (14)
(15) (16) (17), also has an antialergenic action (18) (19), as antitumoral
property (20)(21). Besides has an antiviral activity. (22)
Thriterphenal
Steroids, Steroidal Glycosids, Crisosaponic Acid, Santonine, Absintine, Resinic
Acid, Luteoline, Quercetine, Acacetine, 7,4-dimetil-Apigenine, Cirsimaritine,
Salvigenine, Jaceidine, Esculetine, jaceosidine, Oleanolic Acid, Lupeol,
Chonodrillasterol, Arabionogalactan, Ramnogalacturonana, Grucomanan, Tanines,
Fenocarboxilic Acids. Flavonoids: Apigenol, Luteolosid, Reductant Sugars.
Mineral
saults (Zn, Si, K). Iridoid Heterosids: asperulosids, aucubosids, catalpol.
Solvent
and Excipients.
In vitro studies were made, toxicity studies at
Biochemical Catedra of Chemist Faculty of Buenos Aires University, where was
demonstrated its inocuity.
Besides were made stability studies at Pharmacognosy
Catedra at Chemist Faculty of Uruguayan University, that showed the viability
of the product in time.
After the obtaining of this formulation were started
“in vivo” proofs in animals that made by a Veterinarian Doctor Carlos
Rodríguez, who obtained results with the
one, in this cases were injected peritumoral and sometimes intratumoral.
This way with the results obtained the patients of my
private activity opted to proove this product, obtaining very good results, as
other collegues from more than 14 countries.
Due these ones, it’s why we decide to make scientific
studies in a Official Institute, that guarantee these properties.
For this reason
“in vitro” studies at CEFYBO, dependent of Ministry of Education, Science and technology
dependent of Argentine Republic Presidence.
I. DESCRIPTION:
The anti proliferate action of
GREEN SAP product was evaluated on lymphoma murine cells BW5147 in vitro by dosage-answer curves and at
different times of exposition to these products, in cultures of them in
presence and absence of this herbal extract, of its individual components or
the vehicle. The proliferate answer was
determined by the technique of [3H]-timidine ([3H]-TdR)
incorporation to cellular DNA and later evaluation of the nuclear radioactivity by spectrometry
of liquid twinkle.
II. METHODOLOGY’S
ESPECIFICATION :
1- Herbal Extracts :
The herbal extracts evaluated correspond to the following description:
1- Mother Tincture
(MT): Correspond to a tincture made by the mixture of three individuals
tinctures, to know: Baccharis articulata’s tincture 40 % v/v; Rosmarinus
officinalis’s tincture 40 % v/v and Plantago major’s tincture 20 % v/v. The
alcoholic content of mother tincture is of 50 %.
2- Final Product 1 (FP1) or GREEN SAP: Correspond to a
dilution 1/10 of mother tincture in
water (Baccharis articulata’s tincture 4 % v/v; Rosmarinus officinalis’s
tincture 4 % v/v , Plantago major’s
tincture 2 % v/v and alcoholic content of 5 % v/v).
3- Final Product 3
(PF3): Correspond to a dilution 1/10 of
mother tincture, with an alcohol aggregate till a final concentration of 15 %
v/v.
2- Lymphoma murine line:
3-Conditions of culture and
evaluation of cellular proliferation:
The cells BW5147 (3-5 X 105
cel/ml) were cultured in medium RPMI 1640 supplemented with 10% of bovine fetal
serum and 2 mM of glutamine in presence of antibiotics penicillin (100U/ml)
and streptomycin (100µg/ml), in plates
of 96 cups (final volume 0.2 ml),
in conditions of sterility (laminar
flux, Sterilized Guard Hood class II, Type a/B3; mark: Baker Company, model:
SG-400m), and in gasified ambient with 5% of CO2 (gasified stove of
CO2; mark: Scientific form; model:
3111). It have been made cultures with increased concentrations of the herbal
extracts already mentioned for 24, 48 and 72 hs of incubation. The cells were
pulsed with 0.75 µCi/cup de [3H]TdR (S = 25 Ci/mmol) 16 hs before
the sacrifice of cultures (by freezing at -20 ºC).
Later the cultures were unfreezed and
filtered by glass fiber’s filters, Whatmann GF/A. The [3H]-TdR incorporated to nuclear DNA and stopped in
these filters was quantified by spectrometry of liquid twinkle using cocktails
of commercial twinkles. The results (obtained in dpm) were expressed as
Percentage of inhibition (% Inhib) considering as 100% a the dpm obtained in
absence of extract and/or in presence of vehicle.
4-
Determination of cellular viability:
The cellular viability in different times
in presence or absence of MT and FP was evaluated by microscopic cellular count
in Neubauer’s camera, using a colorant of exclusion, the Blue Tripan. The correspondents % of viability
were calculated taking into account the quantity of alive cells (that don’t
include the exclusion colorant) with respect to the total cells (Alive + Death,
just to say the cells that incorporate the colorant and are seen blue colored
at microscopic observation).
5- Statistic analysis of results:
The results were analyzed by the
Student’s Test and Varianza Analysis followed by Dunnet’s test to determine the significant differences
between groups. The values were considered
statistically significant when p £ 0.05.
1.
Action anti-proliferate
dosage-answer of herbal extracts on cells BW5147 at 24 hs’s culture:
TABLE 1:
Percentage of proliferate inhibition of lymphoma T cells induced by increased
concentrations of GREEN SAP, of its mother tincture and of FP3, at 24 hs of
culture.
DILUTIONa
|
MT
|
DILUTIONa
|
FP1
|
FP3
|
|
% Inhibb |
% Inhibb |
% Inhibb |
||
|
1/25 |
93.3 ± 2.9* |
1/2.5 |
N.D. |
N.D. |
|
1/100 |
79.5 ± 5.9* |
1/10 |
84.7 ± 3.6* |
85.3 ± 3.9* |
|
1/250 |
60.3 ± 2.5* |
1/25 |
71.4 ± 3.1* |
71.1 ± 7.7* |
|
1/500 |
51.5 ± 3.4* |
1/50 |
44.4 ± 5.2* |
45.0 ± 4.0* |
|
1/1000 |
30.8 ± 3.5* |
1/100 |
23.7 ± 5.1* |
49.0 ± 2.5* |
|
1/2000 |
22.2 ± 3.7# |
1/200 |
17.0 ± 2.5# |
28.7 ± 2.4* |
|
1/4000 |
10.7 ± 1.1 |
1/400 |
5.1 ± 0.9 |
22.7 ± 2.6# |
|
1/8000 |
6.0 ± 0.7 |
1/800 |
1.1 ± 0.8 |
5.2 ± 0.5 |
a There were used correlatives dilutions of MT and FP according to its
proportion in MT. The total volume of dilution of herbal products added
was 0.02 ml, maximum volume that can be added without diluting the
contribution of nutrients in the culture medium. It must be remarked that for
this reason hasn’t been evaluated (N.D. = not determined) the dilution FP1 and
FP3 (1/2.5) is equivalent to dilution 1/25 of MT.
b The percentages of
inhibition were calculated considering as 100% the radioactivity of [3H]-TdR
incorporated in basal cultures (to say,
in absence of herbal product): 24024 ± 1206 dpm. It’s remarkable that the presence of 1.5 and
2 % of alcoholic vehicle (alcoholic content of the dilution 1/25 of FP3 and of
MT respectively) stimulates cellular proliferation in about 25 % . All the
others dilutions of herbal extracts were made maintaining a constant final
concentration of alcohol of 0.5% that didn’t affect basal proliferation. The
results showed are the average ± E.S. of n=5 experiments made by triplicate.
* Defers significantly from the
basal with p £ 0.01
# Defers
significantly from the basal with p £ 0.05
2.
Action dosage-answer of
individuals tinctures on the proliferation of BW5147 cells at 24 hs of culture:
TABLE 2:
Effect of increased concentrations of individuals tinctures on BW5147 cells.
DILUTIONa
|
PLANTAGO (P)
|
CARQUEJA (C)
|
ROMERO (R)
|
|
% Inhibb |
% Inhibb |
% Inhibb |
|
|
1/25 |
26.0 ± 0.8# |
56.8 ± 6.5* |
92.0 ± 2.8* |
|
1/50 |
13.8 ± 8.6 |
38.5 ± 2.5* |
85.8 ± 5.1* |
|
1/100 |
1.5 ± 0.3 |
24.8 ± 7.2 |
70.0 ± 8.5* |
|
1/500 |
1.4 ± 0.1 |
1.6 ± 0.1 |
1.6 ± 0.1 |
a Each extract of
individual tincture was diluted in culture’s medium containing a final
concentration of alcohol of 50% and in the same proportions that are contained
in MT. In the plate was made a positive control correspondent to the dilution
1/25 of MT with the one was obtained in all the cases a % Inhib ³ 94%.
b
The percentages of inhibition showed are the media ± ES of n=2
determinations made by triplicate and were calculated as was explained
previously.
* Defers significantly from the basal with p £ 0.01
# Defers significantly from the basal with p £ 0.05
3.
Action anti-proliferate
dosage-answer of herbal extracts on BW5147 cells at 48 hs of culture:
TABLE 3:
Percentage of inhibition of lymphoma T cells induced by increased
concentrations of GREEN SAP, of mother tincture and FP3, at 48 hs of culture
DILUTIONa
|
MT
|
DILUTIONa
|
FP1
|
FP3
|
|
% Inhibb |
% Inhibb |
% Inhibb |
||
|
1/25 |
99.4 ± 0.1* |
1/2.5 |
N.D. |
N.D. |
|
1/100 |
99.4 ± 0.4* |
1/10 |
98.8 ± 0.9* |
99.5 ± 8.0* |
|
1/250 |
91.2 ± 0.8* |
1/25 |
97.4 ± 6.4* |
98.8 ± 7.0* |
|
1/500 |
80.0 ± 0.5* |
1/50 |
86.4 ± 2.7* |
87.5 ± 6.0* |
|
1/1000 |
38.8 ± 0.9* |
1/100 |
31.0 ± 0.4* |
73.7 ± 1.2* |
|
1/2000 |
25.1 ± 1.1* |
1/200 |
13.8 ± 1.1# |
30.6 ± 2.0* |
|
1/4000 |
9.7 ± 0.2 |
1/400 |
11.5 ± 3.8 |
24.0 ± 2.1* |
a There were used correlatives dilutions of MT and FP as was described in
Table 1.
b The percentages of
inhibition were calculated taking as 100% the radioactivity of [3H]-TdR
incorporated in basal cultures: 32360 ± 1165 dpm. At 48 hs of culture weren’t observed
significant differences with con 1.5% and 2 % of alcoholic vehicle (dilution
1/25 of FP3 and MT, respectively) respect to basal proliferation. All the other
dilutions of herbal extract were made maintaining a constant final
concentration of alcohol of 0.5% that didn’t affect the basal proliferation.
The results showed are the average ± E.S. of n=5 experiments made by
triplicate.
* Defers significantly from the
basal with p £ 0.01
# Defers
significantly from the basal with p £ 0.05
4.
Action anti-proliferate
dosage-answer of herbal extracts on BW5147 cells at 72 hs of culture:
TABLE 4:
Percentage of inhibition dosage-answer induced by GREEN SAP, its mother
tincture and FP3 on the proliferation of
lymphoma T cells at 72 hs of culture.
DILUTIONa
|
MT
|
DILUTIONa
|
FP1
|
FP3
|
|
% Inhibb |
% Inhibb |
% Inhibb |
||
|
1/500 |
54.1 ± 6.8* |
1/50 |
61.2 ± 6.8* |
64.5 ± 5.1* |
|
1/1000 |
49.0 ± 4.0* |
1/100 |
40.1 ± 2.8* |
46.0 ± 4.6* |
|
1/2000 |
39.3 ± 3.1* |
1/200 |
20.6 ± 1.1# |
26.1 ± 3.0* |
|
1/4000 |
29.0 ± 4.8# |
1/400 |
19.4 ± 1.7 |
28.8 ± 1.7* |
a There were used the
correlatives dilutions of MT and FP as was described previously.
b The percentages of inhibition
were calculated taking as 100% the radioactivity of [3H]-TdR
incorporated in basal cultures: (16781 ± 1188) dpm. In all the dilutions was
maintained a 0.5% of alcoholic content that didn’t modified the basal
proliferation.
The results shown are the average ± E.S. de n=5 experiments made by
triplicate.* Defers significantly from the basal with p £ 0.01#. Defers significantly
from the basal with p £ 0.05
5.
Action of herbal extracts on
the viability of BW5147 cells at different times of culture:
TABLE
5: Effect of MT and FP3 on the viability
of cultures cells at different times of the study
TIME
(hours) |
% VIABILITYa |
|||||
MT
|
FP3
|
|||||
|
1/500 |
1/2000 |
1/4000 |
1/50 |
1/200 |
1/400 |
|
|
24 |
61.3 ± 10.9# |
84.7 ± 5.1 |
71.7 ± 2.0 |
72.5 ± 11.4 |
72.0 ± 6.6 |
85.6 ± 4.5 |
|
48 |
50.3 ± 11.3* |
80.3 ± 4.1 |
76.7 ± 0.6 |
49.0 ± 9.8* |
77.0 ± 3.3 |
76.7 ± 2.9 |
|
72 |
34.3 ± 1.0* |
76.7 ± 1.9* |
84.3 ± 2.8# |
24.3 ± 1.2* |
60.4 ± 2.3* |
80.6 ± 2.8* |
a
The % of viability at each time (average ±
ES of n=3 experiments) were calculated taking into account the quantity of
alive cells (that not include the exclusion colorant Blue Tripán) respect to
the total cells (alive + death: cells that incorporate the colorant and are
seen of color blue at microscopic observation). The results are compared with the
averaged values correspondent to the basal and to the incubated cells by the
same times in average with 0.5% of alcohol, which are detailed at
continuation: (95.3 ± 1.2) %, (94.0 ±
1.4) % and (94.3 ± 1.0)% at 24, 48 and 72 hs, respectively.
* Defers significantly from the
basal values with p £ 0.01
# Defers
significantly from the basal values with p £ 0.05
CONCLUSIONS:
1-
It’s observed an inhibitory
effect (Fig. 1-3, Tables1, 3 y 4) of the proliferation of lymphoma T murine
BW5147 cells induced by herbal products MT, FP1 and FP3. This effect is
concentration dependent. It’s observed in the 3 times studied, 24, 48 and 72 hs
of culture. It’s maximum at 48 hs of culture to the highest dosage and it’s
seen a potency action at 72 hs of culture of the effects induced by the bigger
dilutions. In this time it must be considered however the possible contribution
to inhibition mechanisms by contact between the cells in culture, that
duplicate every 12-14 hs (Cremaschi et al, J. Neuroimmunol, 2000, 110: 57).
2-
It’s been found concordance
between the effects exercised by FP and MT, in the three times studied.
3-
The evaluation of the effects of
the extracts of individual tinctures diluted and tested in the same proportions
that the ones contained in MT, permit to verify a synergic effect of the three
components (Table 2, Fig. 4).
4-
The microscopic observation with
an exclusion colorant permit infer that also FP as MT has a cytostatic effect
at 24 hs that didn’t modified significantly cellular viability, however with
the time it seems to occur a cytotoxic effect that can’t be discharge the
participation of inherent factors to cellular culture (Table 5, Fig. 5 y 6).
Final
Conclusion: Also MT as its FP exercise an anti
proliferate effect overwhelming on lymphoma T BW5147 that justify to prosecute
with the evaluation of their action on the biological behavior in lymphoma.
Figure
6: Effect of final
product 3 (FP3) on the viability of BW5147 cells at different times of culture.
GREEN SAP MECHANISM OF ACTION
The
synergism of the 3 components of GREEN SAP would be the cause of the remarked
anti-tumor effect which has been demonstrated in the practice.
Based
on Raziner’s studies 1992 and Lithander A.´s 1992 we conclude that it has a
beneficial play part against liver carcinogenesis.
One
of GREEN SAP components is used to prevent cases of chronic gastritis,
stomach-duodenal ulcers, diabetes and wounds. This herb is approved by the
pharmacopoeias of
This
component reduces the lipid profile of the patients, this reduction not being
affected by the loss of bilious acids (which present lipids in their contents)
in the lees. Among the proposed mechanisms for the cholesterol reduction the
most important is related to an interference in the reabsorption of the bilious
acids, as well as an elimination of the mucilage in the intestinal reabsorption
of the cholesterol, what promotes its elimination (Goodman y Gilman, 1991).
In
other way, the topical GREEN SAP application, experimentally inhibits the
initiation and progress of epidermic tumors, induced by benzopirens and 7,12
dimetilbenzoantracen with a 40 to 60 % of efficacy, based in Huang M. et al.
1994.
Besides
the continuous administration of GREEN SAP, has a preventive effect on breast
tumorgenesis, experimentally induced with 7,12 dimetilbenzoantracen with an
efficacy next to 47 % (Singletary K. et al. 1991; Singletary K. et al. 1997).
Helvetian’s
researchers from
In
an oncology level preliminary studies have been performed with GREEN SAP
components either south-american and European in citotoxic tests, interactions
being observed with tumor cell’s DNA (its pro-oxidation) and some favorable
results in leukemia, what makes an investigation way promissory in this field
(Arizona, M. et al., 1985; Jorbis B. et al., 1988; Mangelli E. et al., 1996).
Among
the biological actions demonstrated in GREEN SAP can be mentioned in the
digestive system the anti-ulcerous activity in Indometacine ulcer-induced
models which mechanism of action would be based in a lower mobilization of
intracellular calcium (Gamberini and Lapa A. 1992) and the liver-protective and
colagogue action demonstrated by its flavonoids. The entireness of them
demonstrated to improve between a 25 % and a 100 % the survival percentage of
phalloidine intoxicated rats in a 20 mg/kg intravenous dosage.
The
most active resulted hispiduline (Soickee H. and Leng Peschlow E., 1987).
The
synergy among the herbs that compound GREEN SAP, have a marked anti-tumor
effect and a high liver-protective effect.
Also GREEN
SAP presents an stabilization effect on the membrane potentials, which would
benefit the balance so that the cell does not switch its proliferation towards
a malignant.
INVESTIGATION ABOUT THE FLAVONOIDS THAT COMPOSE GREEN SAP
The flavonoids are phenolics composed that are the part not energetic of
human diet. They are found in vegetables, seeds, fruits, etc. They have the non
oxidative and eliminative of free radicals activity. In lots of investigations
has been demonstrated its antiinflamatory, antialergenic effect, and also a
protective role against diseases like cancer.
These chemical substances can’t be produced by the human body, for this
reason must be obtained by the food or in supplements.
The flavonoids contains in its chemical structure a variable number of
hydroxil phenolics groups and excellents properties of iron quelation and
others metals of transition, this gives them a great antioxidative capacity. For
this, they take an esential role in the protection against process of oxidative
hurt, having therapeutical effects in different patologies as cancer.
Their antirradicals free properties acts fundamentally to hydroxile and
superoxyde radicals.
Between the flavonoids we found:
Citroflavonoids: QUERCITIN (the one that will be the center of our
atention as its predominance in GREEN SAP. Hesperidine, naranjin and limoneno.
Isoflavonoids: Genistein and daidzein.
Proantocianidins.
Antocianidins.
Elagic acid.
Catequin.
Kaemferol.
QUERCITIN
Its antioxidative activity is because it is a great remover of free
radicals, exercising a cytoprotective role in danger situations of cellular
damage.
Its antitumoral activity is related with the antimutagenic action
mechanism and antioxidative power that it has.
It has been used in antitumoral eschemes with sinthetics drugs showing a
increase of this activity. Between this studies we account with:
1) Quercitin with Cisplatin increase the efficacy of this
against LXFL529 cells and lung cancer in humans and rats.
2) Quercitin with
Adriamicin potence its activity in cases of MCF-7 breast resistant cells.
3) Quercitin with Busulfan increases to the double the
activity of her in cases of leuchemia mieloide cronic.
Also in tumoral human cells
cultures (colon, estomach and ovary) has demonstrated stop the proliferative
process, afecting the cell in the cicle G1-S of transition phase.(29) (30)
Besides it has been demonstrated its activity at inmunological level,
renforcing it in especial on gastrointestinal tract.
Quercitin’s antioxidative action shows sinergic effects with vitamine C.
Ascorbic acid reduces the quericitin oxidation, so the combination with her
allows the flavonoid maintain its fonctions antioxidatives for more time.
At liver level it has been described that quercitin has an
hepatoprotective effect, preventing lipidic peroxidation, attenuates colagen
deposits and hepatic fibrogenesys process.
PROTOANTOCIANIDINS
At central nervous system, the flavonoids protoantocianidics by its
properties of being liposolubles and hydrosolubles, these can get through
hematoencephalic barrier and this way protect brain cells, that they are
sensibles to the lesions producec by free radicals.
Other property that present these flavonoids is to increase the
efectiveness of natural killer cells of inmunological system.
TREATMENT STAGES.
It
is a personalized treatment which depends on the evolution of each organism
that receives the medicament. It is divided in 5 big stages:
1. Assimilation: it concerns the good
acceptation of the medicament by the patient, generally we must wait to
acquaint this stage 15 days.
2. Contention: it lasts in accordance
to the disease, more or less 3 months. After this stage is finished the
individual’s biochemistry must be performed and its evolution until this moment
is studied.
3. Effectiveness’ valuation of the
product according to the obtained analyses: different variables are presented
such as: A. Reduction of tumor’s size due to its necrosis, if it is these case it is suggested a
maintenance dose of 60 drops twice a day half an hour before meals. B. Partial
reduction of the tumor or in case of metastases, its disappearance or
reduction. It is suggested to keep the actual dosage and in the future
according to the patient’s evolution take new analyses for evaluation
performed. C. Actual improvement of the patient in these cases it is suggested
60 drops once a day in fast in the morning GREEN SAP.
4. If the tumor keeps under control and
the improvement is evident it is recommended 6 months with a dosage of 30 drops
once a day in the morning.
5. Complete remission of the pathology,
patient with actual improvement. We advise at this stage in which the patient
is in a good state of health, the annual ingestion of 30 drops in the morning,
to avoid recurrence of the tumor or tumors or the appearance of metastases.
GREEN SAP is administered under
the tongue, avoiding this way the pass through the liver, being absorbed
directly.
Besides
in case of not being able to administer it this way, can be administered orally,
diluted in orange juice, this is explained by the synergism between the
quercitin (flavonoid present in GREEN SAP) and vitamine C, that potences its
effects. In cases of patients without oral way, it can be administered by nose-to-stomach catheter by syringe
or by stomach-ostomy or jejune-ostomy, making a dilution of 1 cc of phisiologic
serum .
About side effects of this product, we don’t have in
our casuistic of more than 3.000 patients notices about any kind of allergenic
reaction, just be cutaneous or systemic,
digestive, etc.
CONTRAINDICATIONS
As we don’t have any studies about teratogenicity
of the product, it’s not recommended its
application in pregnants as in mothers in lactancy.
Inquiries of some patients treated with the medicament.
This
is the result of the observation and experience in the handling of the
medicament; from which results an anecdotic experience we would like to
transmit.
When
we refer to a clinic cure of a patient we mention his/her present state of
health. We do not take into account classic clinic research time periods in
oncology; because of the nature of our medication and our patients. This is a
revision, a retrospective.
“We
would like to settle down that we have in our possession the consent of the
patients that appear in this work to have their clinic registers published, informed
consent. Anyone who wants to see these patients’ approval as we have mentioned
will have it sent.”
Name: Eber Paiva
Age: 67 years old
Country:
Reason of consultation:
inflammatories and does not improve. This
symptomatology was present since six months ago. The episode of the UAR
motivated his consultation.
Personal antecedents: No
personal antecedents to remark.
Family antecedents: Mother
deceased because of a rectum AC.
Present disease’s
antecedents:
He begins six months ago with polaquiury and
disury which needs the mentioned treatment to be performed. Rectum tactum
performed, prostate compatible with a IV grade hypertrophy. (see page 17).
Biopsy by trans-rectum ultrasonography that
shows well differentiated prostate adenocarcinoma. Gleason 5, PSA 14,94 (see
page 18).
GREEN SAP initiated on November 3rd.,
2001, 40 drops 3 times per day.
PSA after 30 days: 8,21.
It is decided to increase the medicament to 40
drops 4 times per day. He improves the urination disorders (urination stinging)
and testicle pain.
Disease evolution: On
the
Released
patient, ingests the medicament for one month yearly in a dosage of 30 drops
per day.
Conclusions: 67
years old, with no personal antecedents to mark, suffers an urine acute
retention. The biopsy by trans-rectal ultrasonography shows a Prostate
Adenocarcinoma well differentiated Gleason 5, PSA 14.94. GREEN SAP treatment is
initiated on November 3rd., 2001, 40 drops 3 times per day. He
quickly improves his urinary disorders and testicle pain that grieved him.
He
reaches the remision and release thanks to the use of GREEN SAP, which has an
acknowledged efficacy in Prostate cancer.
GREEN
SAP is a medicament of proved efficacy in this pathology, demonstrated along
the years and the empiric experience. It is evident that GREEN SAP avoided more
significant damages in the patient and we can say that it is a medicament for
which this patient lives thankful for having eliminated his illness.
Name: Héctor
Tanco
Age: 66
years old
Country:
Reason of consultation:
Personal antecedents: Hypertension,
treated with hyposodic diet although he does not attach to it regularly.
Smoker
until 30 years ago. No alcohol. Apendicectomized and amigdalectomized, asthma
until 22 years old.
Family antecedents: None
to remark.
Present disease antecedents:
Begins
with polaquiury. Studied with PSA showed figures of 84.5 on the
Prostate
Biopsy Punction under trans-rectal ultrasonographic control. Images compatibles
with: Prostate of 38x41x31 mm. which shows an approximately weight of 34 g. The
specific prostate antigen for that weight would be 4 ng/ml. Cystic image in
retro-uretheral central zone, seminal vesicles symmetric .
Pathological
Anatomy: showed a well differentiated Prostate Adenocarcinoma. Gleason Score 5
(3+2). It is a bilateral carcinoma, the compromise is similar in both sides and
of a 50 %. Date of the result:
Total
bone centellography: Date
Abdominal
and pelvic Computerized Axial Tomography: The liver conserves its habitual
morphology and density, its structure is homogeneous, there is no dilatation of
the bilious way, the bilious vesicle content is homogeneous by this method.
Spleen, pancreas, kidneys and adrenal conserved. At the pelvic area an
increased size of the prostate is observed with of the blade floor, the blade shows its
walls slightly thickened. No lymph nodes retro peritoneal iliac or inguinal are
observed.
Disease evolution: A
treatment with gosereline, 3,6 injectable, monthly, is installed, and
bicalutamide 50 mg. per day. As a definitive pretreatment is installed B.A.T.
We
indicate 50 drops of the medicament, sublingually, every 6 hours.
Normalization
of his free PSA.
Patient
who begins his disease in stage T 2c N0 M0. He took the medicament during a
year, at the present moment he is at clinic remission, taking 30 drops per day
during one month, one month per year. Patient on release.
66
years old, hypertension, treated with hypo-sodic diet, carrying a prostate differentiated
adenocarcinoma, Gleason Score 5 (3+2), with similar compromise of both sides of
a 50 % (
Treated
with gosereline 3,6 injectable during a month and with bicalutamide 50 mg. per
day. A total androgenic blockade is performed, definitive pretreatment.
He
receives the medicament 50 drops sublingually every 6 hours; he reaches the
cure due to GREEN SAP which was the medicament he most received.
There
is normalization of the biochemical parameters which are beneath normal limits.
The
patient leads a life with an excellent quality thanks to the medicament.
GREEN
SAP has an excellent action against prostate cancer and has achieved that this
patient leads a complete life and has eliminated his neoplasy thanks to this
medicament. GREEN SAP has returned to him total functionality and changed his
life, due to its efficacy empirically proved and of first level in prostate
cancer.
.
Name: Raúl
Smith Belgrave
Age: 77
years old
Country:
Reason of consultation:
Night
urine and weak urine flow.
Personal antecedents:
Mesenteric
thrombosis in January,1995. He went under surgery and is evolutioning without
difficulty.
Family antecedents: With
no antecedents to remark.
Present Disease Antecedents:
Because
of the night urine and weak urine flow was attended by an urologist who found
at the rectal digital exam a prostate size increased and hardened of woody
consistence, therefore indicating the following complementary exams which
showed the following results:
Prostate
ultrasonography: Bladder almost empty, anyway prostate size globally increased
and heterogeneous, which measures 55x41. Superior hemi-abdomen ultrasonograph:
fat liver, no nodular lesion, no other alterations.
Bone
gammagraphy: Nuclear bone scan where increased accumulation of the
radio-pharmaco can be seen in the lumbar vertebral column (L5) and reduced
accumulation in both sacroiliac joints.
Prostate
biopsy
Besides
the patient experiments a notable improvement related to the night urine
previously mentioned.
Disease evolution:
It
was not possible to follow through the PSA as there are no reactives in the
country. But the imagenologic studies were repeated on the
Nuclear
bone scan shows larger accumulation of the radio-pharmaco on the fifth lumbar
vertebra subjective of an increased osteoblastic activity at that level.
It is
suggested a conventional radiological study to discard bone degenerative
process, in the rest of the skeleton no other pathological captures can be
visualized.
Now
the patient refers to present only pain in the hip joint.
On
the
All
the complementary exams are within normal parameters. (see Some e-mails
received page 159).
Patient
on real improvement.
Conclusions: Patient of 77 years old proceeding
from
Bone centellography with increased accumulation
of the radio-pharmac in lumbar vertebral column (L5) and reduction of it in
both sacroiliac joints. The
On the 12/09/2003: PSA in 12 ng/l, frank hip
joint pain improvement, receiving a dosage of 40 drops 3 times per day. Patient
on urology and oncology release, with last PSA of 7,4 ng/l. Good general state,
no weight loss and good appetite. All the complementary exams are within normal
parameters. There is no doubt that the benefic effect of GREEN SAP on the
prostate cancer, has manifested totally, conducting to the clinic cure of the
patient, as well as his doctor daughter tells us by e-mail.
This patient achieved the cure of his pathology
thanks to the use of GREEN SAP, that has a proven first level efficacy in
prostate cancers, as well as in lots of others. It supports this testimony the
fact that this patient’s daughter is a colleague who worked in the National
Oncology Institute of Cuba and actually is working in
Name: Luis
Mohana
Age: 72
years old
Country:
Reason of consultation:
Personal antecedents:
No personal antecedents to remark.
Family antecedents: None
to remark.
Present disease
antecedents:
Treated due to bladder polyps, with multiple
explorations. In one of them a prostate increased in size is discovered, having
the patient a normal PSA. In the first Pathological Anatomy can be seen various
fragments of prostate tissue with glandular hyperplasia, ectasy, chronic
inflammation and multiple areas of PIN III with acinar hyperplasia, (see page 57). Results: low molecular weight
queratine positive 95 % and (++). High molecular weight queratine positive in
the area of atypical proliferation. PIN III (Diagnosis: glandular hyperplasia
with micro-areas of PIN III).
Note: No total loss of basal layer is observed
in these areas.
It is indicated control and treatment in
Oncology Urology center in
Disease evolution:
We keep in touch by e-mail or telephone. He
accomplishes the treatment with the medicament precisely and the process keeps
localized. As we do not see the patient we cannot have the perception that
gives clinic exploration, anyway, at the present moment, the patient is within
normal parameters.
Conclusions: Patient
with malignant prostate pathology of 72 years old proceeding from
The pathological anatomy shows
glandular hyperplasia with micro-areas of PIN III, and begins treatment with
the medicament on May 3rd., 2002.
Beginning
with 30 drops, 4 times per day sublingually. Evolution towards an improvement,
keeping always the PSA within normal values. Effect we attribute to the GREEN
SAP. Patient who at present we can consider cured (not with the criteria of 5
years, international criteria) thanks to the use of GREEN SAP, which once again
has shown its nobility as an anti-neoplasic medicament allowing the patient to
be in a good state of health performing the daily activities that any person
can do.
Name: Pablo
Cordero
Age: 88
years old
Country:
Reason of consultation:
Personal Antecedents:
Gonartritis; hypo-acusia.
Family antecedents: None to
remark.
Present disease antecedents:
In
January, 2002, due to an acute urine retention, after being examined he was
given the diagnosis of prostate cancer, he had a bladder endoscopy made towards
the end of March, resulting positive and was indicated Flutamide one tablet 3
times per day. He was suggested an orchectomy, but his family prefers
alternative therapy. He looses weight. Anemic, with no pelvic pain, with
bladder catheter. He underwent a prostate biopsy punction. Anatomy pathology
Diagnosis: A. Prostate, right lobe (biopsy), moderately differentiated
adenocarcinoma, Gleason 3+4=7 which compromises approximately 30 % of the
sample, with no peri-neural invasion.
There’s
a PIN III area of high grade, areas of lympho-vascular permeation are observed.
B. Prostate, left lobe (biopsy), moderately differentiated adenocarcinoma
Gleason 3+4=7 which compromises approximately 20 % of the sample.
No peri-neural or vascular invasion
is observed.
A
month later bone centellography shows compromise, not defining in which bone.
Disease evolution: They decide to use our medicament.
The patient feels well and the catheter was
retired. In the 4th. month of treatment with the medicament he is
urinating normally.
On February 11th., 2003, underwent a
surgery due to intestinal occlusion caused by adherences of an old appendicitis
surgery. He was grave and stayed in hospital for 36 days.
Also due to a pneumonia because of a hospital
bacteria, but he is recovering satisfactorily.
He had a rectal exam done and a pelvic and
abdominal computerized tomography. In the rectal exam a prostate increased in
size but soft was found, as a bubble and not woody. He did not show pain at the
tactum, the CAT showed a somehow big prostate. The surgeon informed that in the
operation area the intestines were metastases free, only some necrosis of the
thin intestine due to adherence was found.
He changes doctor and consults a urology
oncologist, who did not know his case and found a prostate with the size of a
plump.
The prostate was found to be of soft
consistence as rubber and had a little protuberance also soft. He was surprised
by the fact that previously he had been diagnosed as advanced prostate cancer.
The doctor saw the biopsy and confessed that if it wasn’t for it he wouldn’t
have believed it was the same patient.
A bottle of the medicament he was taking is
shown to the doctor. He concluded that this medicament, which was the only
thing he was taking, must have improved his cancer. Anyway he ordered some
laboratory exams and “X” rays, he recommended to go on taking the medicament.
The patient is asymptomatic, in real
improvement. (see Some E-mails received, page 159).
Evidently, as for the collected experience, a
benefic effect of GREEN SAP on prostate neoplasies is found, which is
demonstrated by normalizing or reducing the PSA, causing a loss of size of the
tumors evident either by rectal tactum or by trans-rectal ultrasonographies
explorations, as well as on its consistence which goes from rocky to woody and
from woody to a normal prostate consistence. The particular histological
structure of the prostate can be in the genesis of this interaction which is
hurtful to the tumor. Probably by a antiangiogenic mechanism the
neo-vascularization of the tumor is
prevented, depriving it of essential nourishing factors for its development.
This development has lost control, the cells have lost contact inhibition to
proliferate.
GREEN SAP acts also at cellular level causing
cytotoxicity and a cytostatic effect; occuring tumoral cell death not only when
GREEN SAP is acting but “a posteriori”, generating
an accumulative effect evoluting to tumoral death induced by GREEN SAP.
This is maybe the reason
why we find samples of prostatectomies with important intra-tumor necrosis and
hemorrhages in their way to resolve or organizing; this observation would not
correspond so much with the conventional hormonal treatment generally used.
It was also observed that GREEN
SAP; prevents the creation of new tumor clones that escape to the body’s
control and provoke early metastasis moreover on the bone substance, prostate
metastases have avidity for bones.
Therefore GREEN SAP has a
protective action on the bones preventing this body sector’s colonization by
the disease, we observed osteoblastic lesions treated with GREEN SAP that set
back and are eliminated by the organic depurator systems, provoking a removal
and mobilization of the accumulated substance in the skeleton or particular
areas of it.
The bone centellography
exploration allows to appreciate the differences among treatments before and
after the GREEN SAP.
The hormonal traditional
therapy has the risk of provoking thrombotic pathology.
This is another effect we
see that does not occur with GREEN SAP, when a conventional treatment plus GREEN
SAP is faced, what leads to the patient’s benefit as it frees him of thrombosis
of the lower limbs and other economy’s areas.
Many times this can be the
event that provokes a lung thrombo-embolism, and this can lead to a very
characteristic episode which can lead towards the patient’s death. Knowing the
fact that lung thrombo-embolism is diagnosed by perfusion-inhalation
centellography, in order to appreciate the lung area that ventilates and
therefore the affected one, we can affirm that in conventional-GREEN SAP mixed
treatments, we did not observed it so it does not occur in our casuistic.
Name: Jorge
Lindh
Age: 56
years old
Country:
Reason of consultation:
Personal antecedents:
No
antecedents to remark.
Family antecedents:
We
ignore them.
Present disease
antecedents:
It was thought at the first place that the
neoplasy had been taken definitively, a year later, after two checkinGREEN SAP
that did not show any anomaly, shortly after the third checking, in July, 2001,
he had a thorax additional tomography. At that moment metastasis in both lunGREEN
SAP were discovered. Lymphatic metastasis in left and right lung which oppress
both the tracheas and the esophagus. Later on it was discovered an additional
metastasis in the left kidney post-surgery lay and behind the right clavicle.
He consults about the possibility of treating himself with our medicament.
Disease evolution:
Patient who was treated only with our
medicament by his own will.
The metastasis behind right clavicle also
stopped its growth.
The lunGREEN SAP metastasis which oppressed
tracheas and esophagus only have grown 10,14 mm, he does not have swallowing
difficulties.
He maintained his weight. Normal kidney
functionality. Marginal tumor growth, it is increased to 50 drops 4 times per day.
The patient improves his life quality, he can
perform a normal life ambulatory, he goes on with 50 drops 4 times per day
having his next control in May.
He is asymptomatic in real improvement and is
released with a maintenance GREEN SAP dosage.
Conclusions:
Patient of 56 years old, left kidnectomized in
1998 due to a malignant kidney pathology (light cell kidney adenocarcinoma),
surgery in
Name: Jorge
Antonio Suárez
Age: 51
years old
Country:
Reason of consultation:
Asymptomatic until March, 2001.
Personal antecedents:
No personal antecedents to remark.
Family antecedents:
No family antecedents to remark.
Present disease
antecedents:
Asymptomatic patient until March, 2001 when he
presents a left iliac fossa tumor, he has a biopsy done which shows a light
cell carcinoma.
Clinically asymptomatic.
Computerized tomography: right supra-kidney
gland metastasis. Nodular lesion in contact with the posterior side of the
lower cava vein. Nodular lesions that compromise the psoas muscle.
He had a computerized tomography of the facial
cranium structure done, which was normal.
Neck computerized tomography: normal.
Thorax computerized tomography: nodular image
of soft parts density of approximately 15 mm in maximum left posterior
intercostals diameter which would have to be evaluated following the
antecedents.
Pelvic abdominal computerized tomography: it
were explored the pelvic and abdominal regions, after the intake of oral
contrast substance to dye the digestive tube and the injection of contrast
substances intravenously.
Discrete diffuse hypo-density of the liver
parenchyma compatible with slight infiltration. Nodular images compatible with
metastasis in the right supra-kidney gland. The biggest of them of
approximately 35 mm. It is also observed nodular lesion in contact with the
lateral side of the lower cava vein immediately above the right kidney vein.
Sequel of left kidnectomy, being identified the pancreas tail and the lower
pole of the spleen at the kidney fosse. It is observed nodular lesion in the
upper pole of the right kidney. The gall bladder does not show any alteration.
The left supra-kidney gland is not identifiable. Nodular lesion with cystic
and/or necrotic center coming from the front area of the left psoas muscle. It
can also be observed nodular confluent lesions with soft parts density which
involve the left iliac psoas muscle. It is also identified a nodular lesion in
the right internal obturator muscle.
Comment: The described lesions in the thorax
and specially in the abdominal-pelvic region are compatible in first place with
metastasis.
Disease evolution:
He initiated the treatment with the medicament
in November, 2001, with 45 drops 4 times per day. After a month he continued
with 50 drops. Next month 60 drops 4 times per day.
He goes on with 60 drops every 6 hours
sublingually.
Conclusions:
Patient of 51 years old, left kidnectomized.
Asymptomatic, until March, 2001. In March, 2001 presents a left iliac fosse
tumor which shows in the biopsy Light Cell Carcinoma. He also presents
in the computerized tomography a nodular image with soft parts density of 15
mm. of intercostals maximum diameter.
Lesions compatible with metastasis in the right
supra-kidney gland.
He initiated treatment whit the medicament in
November, 2001, quickly evolutioning both clinic and imagenologically.
The GREEN SAP’ mechanism of action on the
kidney tumors and its metastasis manifested once more leading the patient to
the clinic cure and his release. Maintaining a control dosage with the
medicament.
This patient is in healthy state, what we
attribute to the use of GREEN SAP, which has acted as we have been seen for
years, in an excellent way. GREEN SAP is a therapeutic weapon of first level
and our patients are our witnesses of the seriousness with what we face our
work with them and we believe that this medicament is a fundamental
contribution to the contemporary medicine. (see Conclusions GREEN SAP’ action
on kidney neoplasies, page 89)
Name: Irma
Renoldi
Age: 65
years old
Country:
Reason of consultation:
Personal antecedents:
Without personal antecedents to
remark.
Family antecedents:
None to remark.
Present disease
antecedents:
She begins with lower limbs edema a month ago
reason why she underwent exams. The abdominal ultrasonography and
abdominal-pelvic and thoracic CAT show a left kidney mass. The CAT informs
retroperitoneal mass that measures 5,1 cm. That seems to originate in the back
valve of the left upper pole extending to the medial area getting in touch with
the diaphragm and also with the left kidney vein. The bone centellogram does
not show metastasis. The treatment with the medicament is initiated taking 40
drops 4 times per day.
Disease evolution:
We maintain 40 drops 4 times per day
sublingually. We maintain such dosage until December, 2002.
At the present moment, due to the complete
reducing of the tumor mass and the excellent clinic and paraclinic state we
release her with real improvement, maintaining basal dosage of the medicament
during a month, once a year.
Conclusions:
Patient of 65 years old, who consults because
of a retroperitoneal tumoration. The CAT shows retroperitoneal mass which
measures 5,1 cm., that seems to originate in the back valve of the left upper
pole, extending to the medial sector getting in touch with the diaphragm and
also with the sub-renal gland. It also contacts the kidney vein.
She initiates the treatment taking 40 drops 4
times per day. GREEN SAP, due to the explained mechanisms in the kidney anti-tumor
action, acted in a quick and effective way, achieving the patient’s clinic cure
and her release, who presented a voluminous and related to other structures in
the vicinity, kidney tumor.
GREEN SAP stopped the tumor kinetic, leading
the patient towards a healthy state that more expensive medicaments and with
more disgusting collateral effects and medicament interactions do not achieve
in a indolent way, that is without suffering as our medicament does which has
the back up of the cases in which it has achieved complete remissions, clinic
cures and over all, what more interests us, an excellent life quality that
allows the patient to develop from a physical point of view in a completely
normal way, what psychologically benefits him in a superlative way, this being
many times forgotten by the traditional medicine, but we keep in mind every day
focusing the patient as a whole.
GREEN SAP deserves a stand up position among
the medications which fight malignant diseases and make so without causing
collateral effects, which many times in traditional medicine oblige to give up
the treatment, which in a very high percentage of cases this does not happen to
us, also establishing through GREEN SAP an actual friendship with the patient,
what encourages him to go on and achieve the improvement as in this case, in
which this medication was used.
Name: María Alejandra Tabares
Age: 4
years old
Country:
Reason of consultation:
Personal antecedents:
No personal
antecedents to remark.
Family antecedents:
No family antecedents to remark.
Present disease antecedents:
Next Tuesday,
Microscopic
description: In the histological cuts a malignant tumor lesion is identified
formed by a blastomatose component, an epithelial one, forming tubular
structures, and others mesenquimal-fusiforms. It is not observed anaplasy
characteristic. The tumor compromises the kidney capsule but does not perforate
it.
In
the not tumor kidney parenchyma there is tubular atrophy.
It
is not observed neither compromise of the vein nor the kidney arteries nor the
urether.
It
is a Wilms’ triphase tumor, with favorable histology, compromise of the kidney
capsule without perforating it. Resection border lines vascular and urethral
free of tumor. Following the results obtained from pathology, chemotherapy
treatment was determined, with a protocol of 18 weeks with Vincristine, 0,05
mg/kg/d. Treatment followed until the week 10. Actinomicine D 0,045 mg/kg/d
every 3 weeks until the week 18. Such treatment was initiated on February 22nd.,
2002 and ended on June 22nd., 2002. During the chemotherapy
treatment, control exams were performed, such as thorax Rx, hemograme,
creatinine, etc. Very satisfactory results were obtained from surgery and
chemotherapy.
On
October 25th., 2002, a new control abdominal scan was performed and
the following results were obtained:
Multiple
cuts were made axially, and with helicoidal technique in abdomen, from lung
bases to pubis sinfisis in simple phase and with 8 mm thickness cuts. The study
was solicited without contrast mediums.
Findings:
Changes in left kidnectomy are identified. The left kidney fossa is empty and
the tumor observed in the left kidney has been completely extirpated, the
kidney fosse is occupied by thin intestine asas, although without contrast it
is difficult to evaluate the retro peritoneum, in the present cuts there is no
evidence of tumor recidivisms.
It
is surprising towards the left supra-renal gland the presence of a hypo-dense
image of low density which could represent either a residual tumor or an
adrenal gland lesion. There is no pleural drain or nodular images. The
observation of the liver is normal, without metastasic disease. There is no
evidence of gall via intra or extra liver.
Coledoco
and gall bladder normal.
Spleen,
pancreas, right supra-renal gland and right kidney without alterations. There
is no evidence of masses or retro-crural or retro-peritoneal
lymphadenomegalies.
Cava vein and aorta: normal.
No collections or ascitis liquid are observed.
In
the pelvis are identified the urinary bladder, rectum and annexes normal.
There
are no pelvic lymphadenomegalias.
Radiologic
conclusion:
Kidnectomy
with complete resection of the neoplasy observed in the previous study
Hypo-dense
lesion in left supra-kidney gland to consider residual tumor or metastasic
disease. There is no evidence of metastasic disease in another abdominal place.
Disease evolution:
On
the past November 7th., 2002, surgery was performed, finding a new
tumor en left supra-kidney gland with a necrosed part attached to the
supra-kidney gland reason why its complete resection was made and the tumor was
again sent to pathology for its evaluation.
Sample:
Left supra-kidney gland.
Macroscopic
description: product of the resection of
supra-kidney gland is received, which weighs 16 g and measures 5,5x3,8x1,2 cm.
Supra-kidney gland is recognized, and in the periphery an hemorrhagic node is
found, lobated, partially cystic and hemorrhagic which measures 1,8x1,6x1,6 cm,
it is partially opened in the same container and separately they come several
segments of tissue brownish colored, breakable consistence which weigh 1 g.
Representative cuts are processed.
Microscopic
description:
In
the histological cuts supra-kidney gland is identified which presents in its
capsule and fat that surrounds it, primitive tumor lesion, formed by an area of
blastomatose aspect and others with tubular formations. The tumor has quite a
mitotic activity. The material which comes separately corresponds to tumor
fragments partially necrotic which surround striated muscle.
Diagnosis:
Left
supra-kidney gland: Supra-kidney gland-ectomy. Recidivated Wilms’ tumor.
The
post-surgery recovering is very satisfactory, the girl is en excellent state of
health in spirit and nutritionally. She weighs 16 kg. Reason why it is observed
that the tumor did not have any metastasis in other places.
She
goes on taking the medicament until present. She is in excellent state of
health, in spirit, and develops all the activities of a kid of her age.
Asymptomatic, at the present moment is on release and considered with real
improvement. An annual maintenance with GREEN SAP is done.
Conclusions:
Patient of 4 years old, proceeding from
She begins taking the medicament on
In the case of a girl we have to think in her
tiny world, we have to take into account the cruelty of the disease that
grieves her and we have to commit not to add more suffering although this was
justified to improve her, as this can be something that marks all her life. GREEN
SAP Drops, is an innocuous medication, without collateral effects and no
interactions. Easy to take also by a 4 year-old girl, who does not reject it.
It is not traumatizing and its effect is so
powerful as the conventional druGREEN SAP’ one, that is why we consider of such
an importance the GREEN SAP treatment in children, being this an example that
clarifies us about the tolerance and positive effect of the medication that
ends with the patient in clinic cure and on release thanks to GREEN SAP.
We do not know if it can be said of another
alternative medicament of similar or different characteristics, what this staff
can say of GREEN SAP by its empiric experience and years of work, mitigating
the pain and achieving cures where everything was taken for lost.
GREEN SAP action on kidney
neoplasms is highly specific, acting in a selective way on the tumor cell, with
no adverse effects on the benign cells.
Basically has a pattern of
action similar to the one seen on prostate. There would be an inhibition of
tumor angio-genesis, depriving the tumor of nurturing factors, inhibition of
the metastasic production by receptor blockage in different areas of the body
and by direct litic action on the metastasic cell. Acting on the membrane
potentials achieving a broad cell permeability, reason why the cellular
apoptosis is produced.
GREEN SAP effect is very
beneficial on lung metastasis, very frequent in kidney cancers. It acts by
inhibiting the metastasis growth and reducing their number. Comparing thorax
and upper abdominal CATs before and
after GREEN SAP use what was said is proved.
GREEN SAP does not affect
neither the kidney function nor the azoemy, creatininemy, or creatinine
clearance. It does not cause tubular damage. Its components act synergic and
selectively o the tumor cell by the mechanisms already mentioned.
The medicament acts on the
selected clones (the ones which will metastatize) and blocks the areas where
they implant, such as: lung where lots of kidney cancers’ metastasis are seen.
GREEN SAP is an immunity
stimulant, increasing the number of leucocytes specially granulocites, which
benefits the organism to reject tumor pathology.
It stimulates the cilia
sweeping in the lung what benefits the expulsion of strange materials from the
lung, either cancerigen or pre-cancerigen.
It stimulates the
hematosis, this is, the blood oxygenation in the lunGREEN SAP therefore
increases the quantity of oxygen it can grasp and carry the hemoglobin by the
body. A very benefic property as it reduces the risk of hypoxic complications
due to the metastasis in kidney cancer.
Many times the tumor cells
can be driven to zero kinetic, this is, to a quiescent state, of no
reproduction, no proliferation, staying the tumors stables for years, without
growing through all that time, without disappearing either but maintaining the
patient asymptomatic and with an excellent life quality.
It is recommended once on
release, and achieved the clinic cure, the intake one month per year of 30
drops daily, as a maintenance treatment. The basis of this is that if one cell
escaped of zero kinetic, to proliferate and reinitiate the cancer process,
there would be a “sweeping” by GREEN SAP action, or by the medicament
metabolites which have been produced.
We conclude that GREEN SAP
is a first line weapon in kidney cancer treatment, would it be with or without
metastasis, being a natural medicament, innocuous and without collateral and
adverse effects at the recommended dosages.
Name: Eduardo
Benegas
Age: 5
years old
Country:
Reason of consultation:
Endo-cranial hypertension, due to hydro-cephalia
and a brain expansive mass situated in right ganglio-basal area with extension
to cuadrigeminal area.
Personal antecedents:
No special antecedents.
Family antecedents:
Without family antecedents to remark.
Present disease
antecedents:
It was urgently performed an external
ventricular derivation and afterwards partial resection of the tumor that was
informed as anaplasic glyoma.
Disease evolution:
He underwent plain dosage of radio and
chemotherapy. A computerized tomography in October shows good evolution of his
neoplasic lesion and his hydro-cephalia which was treated with internal ventriculo-peritoneal
derivation.
In December, 2002, progressive neurological
deterioration. Left hemi-paresia F.B.C. and control resonance shows extended
ventricular recidivism.
On December 16th., 2002, he
underwent new surgery and subtotal removal of the lesion.
It is desirable to know the inform referring
to: New irradiation? Chemotherapy with temosolamide? Brachitherapy? Other
alternative druGREEN SAP? Another procedure?
Our answer was: treatment with the medicament
at the dosage of 10 drops 4 times per day, the following month we increase the
dosage to 20 drops. This treatment was done at the same time that an strict
vegetarian diet and temodal, indicated by
The present state of the boy (March 3rd.,
2003) is optimum. Energy and vitality intact. Clinic and neurologic state
impeccable. He will go on with the treatment with the medicament.
At the present moment he is in excellent state
of health. Remission of his symptomatology reason why we opt to release him,
due to his present improvement and go on with controls and maintenance dosage
of the medicament.
Conclusions:
5 years old patient, proceeding from
A basal dosage of the medicament is maintained.
It is out of question for us that GREEN SAP has
accomplished a very important role in the cure of this patient. We have
experience in Central Nervous System tumors, of the great efficacy this
medication has.
This boy can have an equal life as that of the
boys without his pathology, thanks to GREEN SAP, which was administered in a
ruled and responsible way. There will always be incredulous people, but for them
we have facts that prove that our medication is of the highest level proved
throughout the years and that in the case of this boy has achieved what many
would consider a miracle.
Name: Mauricio José Ruiz
Age: 8 years old and a half
Country:
Reason of consultation:
In November, 1995, a tumor in the right
hemisphere was detected, which extended from the front pole of the right
temporal lobe (intra-ventricular portion) up to the middle line and back up to
the occipital pole.
Anatomy-pathology: Ependimoma.
Personal antecedents:
No
personal antecedents to remark.
Family antecedents:
No family
antecedents to remrk.
Present disease antecedents:
In August, 2000, he
suffers a recidivism in the same area and he undergoes surgery with total
resection.
Anatomy-pathology:
Malignant Ependimoma.
Post-surgery:
Radio-surgery with 5940 cGy application in 33 sessions of 180 cGy.
In the third
occasion, February, 2002, a nodular image is observed in the left frontal horn.
Treatment:
Neuro-surgery.
Disease evolution:
He starts on April 25th.,
2002, with 3 intakes per day of 25 drops, which were increased to 25 drops 4
times per day in July, 2002.
On
Considering the
tumor, it presents a slight improvement with reduction of the contrast
impression in its borderlines. He is receiving the drops at the dosage
mentioned previously and evidently tolerating them very well with no adverse
reaction. His general spiritual state is good, with great vitality and a normal
activity.
Towards the end of
October, 2003: he will be finishing the 90 days period with a dosage of 25
drops 4 times per day.
The boy is going
regularly to school, asymptomatic. (see Some e-mails received, page 159)
Conclusions:
It is about a 8 years old and a half patient,
proceeding from
It is about a malignant ependimoma which
recidives in August, 2000 in the same place and has surgery done with total
resection. Post-surgery, radio-surgery with application of 5.940 cGy. In
February, 2002, an image in the left frontal horn is observed. It has surgery
done. On April 25th., 2002, starts with 3 intakes per day of 25
drops, which was increased to 25 drops 4 times per day in July, 2002.
Imagenollogically he has improved notoriously. It is
evident that GREEN SAP action crossing the hemato-encephalic barrier and acting
through the various mechanisms with what it generally does and preferably in
the central nervous system, has had a very favorable result.
The result in this patient with the use of GREEN SAP
drops, has been excellent.
Since this patient begins the use of the medicament,
he improved in a very remarkable way. With no doubt GREEN SAP has a prevalent
action on Central Nervous System tumors what places it among the medicaments
that we cannot leave out of question before initiating a treatment. This staff
feels very rewarded by this boy notable evolution and there is no doubt we must
attribute to GREEN SAP such an improvement in a very malignant pathology, of
difficult treatment with conventional drugs that have been used, but we remark
the curative role of GREEN SAP without interfering at any moment with any other
different treatment. The treatment with our medicament has restored the
happiness of life to this boy, without disgusting collateral effects, and we do
not doubt that following with the treatment he will lead a worthy life, as we
all deserve thanks to GREEN SAP.
Name: Sirvart
Doganian de Topalian
Age: 74 years
old
Country:
Reason of consultation:
Brain
tumor
Personal antecedents:
No
personal antecedents to remark.
Family antecedents:
No family
antecedents to remark.
Present disease antecedents:
On
On
On
On 12/23/1999: A new
cranial computerized tomography is done which shows: Signs of left frontal
craniotomy, hypo-atenuating area in left frontal area is observed, in the
borders of the craniotomy, which after the intra-venous injection of yode
contrast, produces annular highlighting. Recidivism? Accentuation of cortical
lines and fissures and cerebella lines. Centro medial structures without
deviation relating the middle line. Slight expansion of the supra-tentorial
ventricular system. Post-surgery control.
On
Observation: Signs of
right maxillary sinusopathy and bilateral sphenoidal.
On
Disease evolution:
She begins to take GREEN
SAP drops at a dosage of 40 drops, 6 times per day in August, 2000.
On
The rest of the
findinGREEN SAP did not alter significantly from the last study.
On 01/30/2001: An
encephalic magnetic resonance is done which shows: conclusions: Post-surgery
control exam of left frontal neoplasy, in relation to the previous exam (from
08/31/2000) it is noted a reduction of the dimensions of
the blood content and the contrast associated of the medium left
frontal lesion and in correspondence to the surgery layer. Slight increase of
the extension of the diffuse signal alteration in the white substance of the
brain hemispheres, of unspecific significance. If there has been radiotherapy
post-actinic leuco-encephalopathy has to be the first diagnose consideration.
On
No evidences of local
neoplasic recidives have aroused.
On
Presence of magnetic
susceptible articles in the craniotomy area which may give partly the adjacent
structures image.
On
Magnetic susceptible
artifacts adjacent to the craniotomy. Peri-vascular spaces extended. There
persist extended areas of signal alteration, characterized by a high sign in T2
and Flair that does not present post-contrast highlighting, compromising the
white substance of both brain hemispheres. Suggesting post-actinic alterations.
The rest of the encephalic parenchyma with normal sign intensities.
Crane-vertebral transition without abnormalities. Extended cortical lines. Big
Silvian caesuras and basal cisterns. Dilatation of the supra-tentorial
ventricular system, IV ventricle with normal form and dimensions.
Comparatively to the
previous exam, reduction of the extension and intensity of the signals of the
post-contrast highlighting areas was observed adjacent to the left frontal
craniotomy.
Cranial magnetic
resonance was made on
We must remark that
the patient received in all this period GREEN SAP drops as medicament, finding
herself as it arises from the imagenologic results, stable since 2 years and a
half ago with the intake of the medicament. Although the tumor extirpation was
performed we think that this therapy alone does not justify the excellent
evolution she had afterwards, reason why we consider her asymptomatic in real
improvement, receiving maintenance dosage of the medicament.
Conclusions:
It is about a patient
of 74 years old at present, with a brain malignant neoplasy of ominous
prognosis. This neoplasy was extirpated, turning out to be a oligodendroglioma-glioblastoma, the patient in the
2000 begins to take the medicament, maintaining unchanged the imagenology and
with a tendency to reduction. GREEN SAP evidently acted crossing the
hemato-encephalic barrier as we stated in the central nervous system GREEN SAP
anti-tumor action. This appears evident by the excellent result achieved as in
the other cases already referred. This is why that a direct GREEN SAP action on
the tumor is observed, although before we did not have the experience we
nowadays have and was stated that GREEN SAP could not cross the
hemato-encephalic barrier as well as many other medicaments.
Nowadays, with the
acquired experience and the results achieved by the patients, we firmly think
that GREEN SAP has a very well deserved position in the treatment of the
Central Nervous System tumors, obtaining remissions, stabilizations and clinic
cures. It is remarkable that no endo-cranial hypertension syndrome has
produced, and this would be related to the mass effect taken away by the
surgery, but also to the anti-inflammatory and stabilization effect of GREEN
SAP.
This is a case that
fills us with proud. The use of our medicament, which has already been proved
by time and the empiric experience, has led a very difficult prognosis patient,
even with the more modern conventional techniques, to a state of health. At the
present moment she is in real improvement and can perform the tasks that other
people of her age develop. GREEN SAP is a medicament of proven efficacy, even
in so dangerous diseases and recommendable in oncology pathology. We can affirm
this medicament is a so fortunate finding from the medical point of view that
enables us to have such rewards as the one offered by this patient. This
medicament is not an improvisation and hundreds of cases all around the world
testify so. It creates hope where there is hopelessness, creates strength where
the body and the soul weak and from the medical point of view achieves a
percentage of cure that plenty justifies what we previously said.
The
central nervous system tumors always have attracted physicians curiosity, as
for their symptomatology, bad prognosis, therapeutic aggressiveness, and/or
many times invalidating sequels.
From
children to aged people, suffer from this pathology that by the other hand
consist of lots of kinds and sub-kinds of tumors that is out of the case to
mention.
Apart
from the primary pathology of the central nervous system, there is its
metastatic pathology, knowing that a high number of tumors metastatize in it
and some of them with special avidity for this area.
GREEN
SAP has a preponderant role in this kind of tumors’ therapeutic, having
achieved complete remissions and clinic cures with the only use of the drops.
Generally the tools used in these pathologies are surgery with total or partial
extirpation and radiotherapy. This is because lots of chemotherapy drugs do not
cross the hemato-encephalic barrier and cannot accomplish their duty. Sometimes
as for example Metotrexate, they are directly placed intra-tecally. GREEN SAP
cross easily the hemato-encephalic barrier, being able to act “in situ” on the
tumor or tumors of the different intra-cranial structures. The fact that it is
possible to place a drug in an inextensible cavity is already an advance in the
direct treatment of the tumor or tumors. There is a certain avidity between the
tumor cell and GREEN SAP, which provokes a bilateral lasting contact.
Due
to potential differences GREEN SAP penetrates in the brain malignant process
and perform the actions which in another part of this monograph we referred to.
At
central nervous system, flavonoids protoantocianidins that compose GREEN SAP,
by its properties of being liposolubles and hydrosolubles, may enter hematoencephalic
barrier and this way protect the
cerebral cells, which are sensibles to lesions produced by free radicals.
The
quick action of GREEN SAP necrotizing or destroying these tumors, makes that
the mass effect they produce (by occupying a place in an inextensible cavity,
such as the crane), that gives birth to a very varied set of symptoms and
signs, known as endo-cranial hypertension syndrome, GREEN SAP achieves that
this syndrome does not take place, or if it does, is very much slight than
expected.
There
would be an anti-inflammatory collateral action that would benefit the GREEN
SAP action at this level. The action that performs at the vomit area, it is
also interesting. But what is really interesting is that by reducing the
intra-cranial mass, the pain due to compression and concomitant vascular
dilatation relieves, which produces very intense and difficult to handle with
conventional therapy headaches, what in emergency is generally deplective,
anti-inflammatory and anti-comicial.
GREEN
SAP “per se”, acts directly avoiding or minimizing the endo-cranial
hypertension syndrome because of the reasons already mentioned.
Name: Luis Peralta
Age: 61 years
old
Country:
Reason of consultation:
Personal antecedents:
No
personal antecedents to remark.
Family antecedents:
None to
remark.
Present disease antecedents:
Diarrheic depositions
since a year ago with comes and goes. Since
On
Disease evolution:
At the present
moment, in real improvement, on release, with a maintenance dosage of the
medicament.
Conclusions:
It is about a patient
of 61 years old proceeding from
On 01/09/2002: begins
with the medicament at a dosage of 40 drops, 4 times per day sublingually,
which afterwards is increased to 50 drops 4 times per day.
He achieves total
improvement and we can see GREEN SAP action in a well differentiated lower
rectum adeno-carcinoma.
With no doubt GREEN
SAP with its action contributed to the no appearance of metastases and the
clinic cure of the patient, who also was treated with conventional therapy,
what shows GREEN SAP innocuousness, the high tolerance to it and the lack of
collateral effects which led to the patient’s clinic cure. Remarking it is not
a clinic cure up to 5 years from now on, as we stated at the beginning of this
work, but the expression of the excellent state of health that the patient has
at the present moment.
In this patient GREEN
SAP action is of no doubt. The experience we have indicates us that in his
pathology, is a medicament of first level, achieving complete remissions and a
life status, so important in these patients, very superior, reason why there is
no doubt for us that GREEN SAP has achieved to revert and control the oncology
disease avoiding the dissemination as this work team’s experience throughout
the years we worked with this medicament has seen.
GREEN
SAP action on colo-rectum neoplasies is basically mediated by the already
exposed mechanisms in other neoplasies. The colo-rectum malignant pathology
develops due to many external carcinogens (due to diet) and internal ones (slow
development of benign polyps into malignant neoplasies). GREEN SAP would have
the faculty of taking the malignant cells into a reproductive zero phase
avoiding and stopping carcinogenesis, maintaining the tumor or tumors in non
proliferative phase and avoiding therefore the cancerization of this sectors.
Also
there would be a property that acts on the vascular structures and leads to
tumor necrosis with afterwards tumor expulsion, apart from the intracellular
action acting directly on the DNA and disorganizing its bases provoking apoptosis.
GREEN
SAP penetrates by the cellular membrane and afterwards by the nuclear membrane
due to a membrane potentials alteration mechanism that permeates the malignant
cell and makes it GREEN SAP’ target, which is transported up to the nucleus
from the cytoplasm.
It
provokes too a depuration of the toxins that are in the colon and rectum,
leading to a “cleaning” of toxins that damage and help the carcinogenesis.
Its
immune-modulating action prevents from infections and viral colonizations that
could lead to the development of a neoplasy.
Because
of everything previously exposed we are sure of GREEN SAP action (which besides
improves the general state) as a useful alternative in the colon and rectum
tumors treatment, either being the tumor present or having had it surgery
extirpated.
GREEN
SAP can act together with chemotherapy also in this pathology as it action is
innocuous, with no medicament interactions and free of collateral effects.
Name: Liliana
Calzada
Age: 48 years
old
Country:
Reason of consultation:
Personal antecedents:
Without
personal antecedents to remark.
Family antecedents:
None to
remark.
Present disease
antecedents:
Antecedent
of right lung-ectomy due to esquamous carcinoma (
Disease evolution:
Conclusions:
With no doubt GREEN SAP has benefited the patient who has a grave and of difficult treatment disease, avoiding convulsions (which she had) and achieving a remarkable improvement either in the primitive tumor as in the metastasis. GREEN SAP has a marked anti-neoplasic action in which the GREEN SAP medical staff has a practice of years. The medicament has been of remarkable efficacy in
Name: Honorio
Serafín Pereira Silvera
Age: 48 years old
Country:
Reason of
consultation:
Progressive
disnea.
Personal antecedents:
Intense
smoker.
Family antecedents:
None to
remark
Present disease
antecedents:
He is
studied with a thorax computerized thomography on
Inform:
Immediately above and in front of the right hilium it is observed a solid mass of approximately 5 cm. which
blocks the upper lobar bronchium. Upper lobar athelectasy of that side.
Adjacent caesural pleural enlargement. We do not see other lung lesions nor
pleural leakage. Lymphadenomegalies latero-trachea right, lower and upper.
Sub-carinal and of the pulmonary aortic window. Liver of normal size, shape and
density. Supra-kidney glands, spleen, pancreas and kidneys without alterations.
Rest of the study with no elements to remark.
Fibro-bronchoscopy
from the
Anatomy
Pathology: The examined sections show a malignant epithelial proliferation,
with the morphology of a moderately differentiated epydermoid carcinoma.
Disease evolution:
BPC III B stage.
Tele-cobalto
therapy, plus chemotherapy is done (CDDP).
Control
thorax radiography of
Begins the
In November, 1998:
Begins with the treatment with our medicament, 30 drops 4 times per day. Total
improvement.
The patient at the
present moment (April, 2003) is asymptomatic, in real improvement. On release
from September, 2000.
Conclusions:
It is about an
intense smoker patient, with a lung epydermoid carcinoma, treated with
conventional therapy, radiotherapy and chemotherapy with medium acceptable
results.
He begins with our
medicament afterwards, improving remarkably his general state remaining with a
slight disnea but with a quick disappearance of his symptomatology reason why
he is on release and considered patient in clinic cure.
This demonstrates the
GREEN SAP action in the lung parenchyma and its metastasis.
The patient achieves real
improvement thanks to the use of GREEN SAP as he was catalogued as incurable
patient by conventional medicine. The patient returns to his original city and
only uses GREEN SAP, achieving with this a real improvement that we can
homologate to the clinic cures of conventional medicine (5 years). This
demonstrates the potent GREEN SAP action on the lung parenchyma, depurating it
of the toxins and attacking the neoplasic cell in a surprising way because of
its avidity. This is a case that demonstrates once again the proved efficacy by
GREEN SAP use, curing a disease of such a difficult prognosis, as Broncho-Lung
carcinoma. It is remarkable that the patient develops a normal life, works and
is another success of our medicament.
It
is doubtless the beneficial action of GREEN SAP on LBC and on its metastasis.
It acts by mechanisms already exposed but which are convenient to repeat now. GREEN
SAP acts stimulating the cilia sweeping and therefore helping to depurate toxic
substances that can settle in the bronchium-alveolar tree.
It
has smoke depurating action, either from tobacco or other kind, reducing the
tar and nicotine levels absorbed by the bronchium-lung system.
Due
to its demonstrated anti-infection action it protects the lunGREEN SAP from
repeated infections that by repeating can provoke a fertile ground to the LBC.
Besides its immune-stimulating action acts synergic ally in this sense. In a
attempt to establish a balance among the noxas that damage the lung and the
“immune protectors” trying to promote the last ones so that no disease are
produced.
When
due to pleural colonization, exhudate or trasudate a pleural leakage is
produced, a situation that avoids lung ventilation in different grades due to
the leakage importance, GREEN SAP acts in that level provoking a liquid
reabsorption, avoiding the trasudate and exhudate and changing the liquid
viscosity making it more easily extractable by the evacuator toracocentesis.
This
liquid can contain malignant cells or not, but is a complication that bothers
the patient by favoring respiratory insufficiency.
As
we already mentioned, by acting in the hematosis, GREEN SAP achieves that the
hemoglobin transports more oxygen to the tissues and this is of vital
importance in patients who have the ventilation compromised.
Referring
the encephalic metastasis its action forms part of what we exposed for central
nervous system, taking into account that most of the central nervous system tumors
are metastatic ones and one of the metastatizers is the LBC.
It
also acts on the supra-kidney metastasis by a citotoxic mechanism that we
presume would be direct on a cellular level.
The
LBC so difficult to treat, and potentially curable in early stages, classically
with surgery and radio-chemotherapy, finds in GREEN SAP an invaluable tool, as
its null toxicity, innocuousness and lack of collateral effects, apart from its
high efficacy in the pathology we are referring to, with proved complete
remissions and clinic cures, only by the use of GREEN SAP, makes it a first
class medicament. The lung parenchyma answers favorably to GREEN SAP action,
which reduces by a prostaglandin inhibitor mechanism the peri-tumor
inflammation which is produced in the lung when a tumor is present.
It
acts in the vascularization as in other tumors, but also acts in the
macro-vasculature, “filtrating” the selected clones that want to implant in the
distance to develop carcinogenesis and therefore metastasis. GREEN SAP would act,
as by an adhesion mechanism it would block the crossing over of these cells
towards the circulation. By circulating attached to GREEN SAP the cells loose
their capability of stopping in other organ and therefore develop the
carcinogenesis. Of course that the other mechanisms already mentioned in GREEN
SAP anticancerigen action also act. For everything here exposed GREEN SAP is of
great usefulness and efficacy in LBC treatment of different kinds, with or
without metastasis.
Name: Herminia
Andarnello
Age: 66 years
old
Country:
Reason of consultation:
Personal antecedents:
Without
personal antecedents to remark.
Family antecedents:
None to
remark.
Present disease
antecedents:
She has an
ultrasonography done on
Pancreas in
cephalic region. Nodular solid image hipo-ecoic heterogeneous of 33x29 mm. It
presents two internal micro-calcifications, pancreas body and tail normal
Retro-peritoneum:
nodular solid image, hipo-ecoic of 18 mm. of diameter situated in
peri-pancreatic region (lymphadenopathy). Direct Bilirrubine 1.9, Total 9.8
Transaminases:
GOT 82, GPT 48
Disease evolution:
She passes
away in September, 2002, due to her pathology, remarking the excellent survival
she presented and the graveness of the disease she was suffering from.
Conclusions:
Pancreatic
cancer is a pathology of high lethality and short survival once diagnosed. Of
this patient more than the survival, in time terms, we remark the life quality
she maintained until the end of her disease. Generally the patients suffering
from pancreatic cancer lead a very impaired survival, with a marked general
repercussion and pains in the solar plexum that many times lead to the use of
radiotherapy as a painkiller, with the results that many times this has. GREEN
SAP acted in the pancreatic cell level minimizing the suffering due to its
painkiller effect, offering the patient a worthy and useful survival.
In this
patient it shows us another aspect of its action. By a direct and endorphin
liberating action, it eased the intense pain the patient suffered from, leading
her to the acalmy. It achieved that in an ominous and grave disease, such as
pancreatic cancer, which besides, causes multiple sufferinGREEN SAP, our
patient had a worthy survival, without pain, with a normal intestinal
movilization, without bilio-hematic derivation, having a survival that it is
not frequent in pancreatic cancer. This she owes to GREEN SAP.
Pancreatic tumours
can be from the hexogen or the endogen pancreas, by this we refer
To
the cells that can be affected by a neoplasm. Those of hexogen secretion, for
example: pancreas head tumour, or those of endogen secretion (insulinoma), it
is not the purpose of this monograph to make a medicine treaty, this is why we
will not stop in the classification of pancreatic tumours, but in the effect
that GREEN SAP has on them.
GREEN
SAP acts moderating the pancreatic secretion would this be endogen or hexogen,
it has direct citolitic action on the pancreatic neoplasic cells, by reducing
the tutor vascularization and affect the cancerous DNA provoking disturbs that
make the tumour cell die.
It
is very important the painkiller effect that GREEN SAP has and that is
manifested in this kind of neoplasies very markedly. Generally pancreatic
tumours, specially the hexogen pancreatic ones compromise due to their situation
the solar plexus, causing pains that turn out to be really untreatable even
with plain dosage morphine.
GREEN
SAP, by inhibiting the secretion of inflammation mediator substances and of
prostaglandins, easies the great pain these pathologies cause.
Also
as it has an immune-stimulant effect, delays the neoplasic caquexy so
characteristic of this tumours. Generally it delays the appearance of liver
metastasis and the tumour adhesion to neighbour big veins, which makes them
many times inextirpable, nevertheless GREEN SAP by a direct mechanism on the
tumour cell, maintains the extirpation levels and many times the patient can
achieve a radical surgery (body-cephalic duodeno-pancreatectomy), or a
palliative one (colecisto-yeyunostomy) (stomach-yeyunostomy) that improve the
patient’s quality life, apart from prolonging it and avoiding the bilio-hematic
derivation so common in the pancreas head tumours.
In
endogen tumours by the mechanisms already known, it acts and avoids that
substances like insuline (insulinoma) are secreted, or like in the gastrinoma
which produces a gastrine aberrant secretion.
Name: María
Julia Pilani
Age: 46 years
old
Country:
Reason of consultation:
Personal antecedents:
Without
antecedents to remark.
Family antecedents:
Intense
smokers parents
Present disease
antecedents:
08/15/2000:
Reviewing the patient’s clinical registers, specially the surgery description
and its anatomy pathology, and the result of the centellogram with MIBI which
does not show capture of the radio tracer at the thyroid logia it is necessary
to make a neck ultrasonography to evaluate if with it a glandular residue can
be found, not able to be found centellographically. If no thyroid residue can
be found and considering the histological type of the tumour to treat no yodum
capturer it is considered unnecessary the administration of the high dosage of
therapeutic yodum. Although the patient has the centellography study with yodum
coordinated as a complementary study to evaluate the possibility of residual
thyroid tissue, not observed with the previous study (reason why the patient is
without hormonal treatment), it is believed of convenience to reinitiate
hormonal therapy and make a dosification of calcitonine as tumour indicator and
from the centellography point of view make a DMSA penta-valent (radio tracer
used in these cases to observe lesion extension).
Disease evolution:
Conclusions:
This case
was included in this monograph in order to show the GREEN SAP anti-tumour
action on thyroid. Although we lost contact with the patient and the pursuit is
not complete. By the data we have we know about the GREEN SAP beneficial effect
on the patient and the hormones that were measured. Take a look on the
para-clinic studies. It was about a Thyroid Medullar Carcinoma with carotid
ganglions with massive substitution and para-clavicle with massive
substitution. She started on
This
benefit, that notoriously improved the patient’s life quality as we have been
proving throughout the time, as it is a high efficacy medicament, has been of
great benefit for this patient.
The use of
the medicament favoured her in several medical ways and this is GREEN SAP’
accomplish, as the staff who work with this medication for years has
demonstrated to be of proved efficacy.
Thyroid tumours,
would they be papillar, follicular, medullar or anaplasic, generally
Cause a generous
extirpation, being according to the tumour, total or sub-total
thyroidectomy.
Generally the
follicular and papillar tumours are of slow evolution, whereas the
anaplasic is a great
malignancy tumour that causes oncology urgencies due to tracheal
compression, what
motivates immediate surgery. In the great majority yodum
radiotherapy
is used, radioactive that is of great efficacy if there are residues of the
gland left. GREEN SAP acts as moderator of the residual thyroid secretion in
case there was any, also preventing the appearance of metastasis in the
distance or intra-thyroid, this made by an endocrine action what makes us think
in a hormone mediated action, in which GREEN SAP would act as hormone-like
allowing to maintain acceptable levels of thyroid and parathyroid hormones,
knowing that many times during surgery the para-thyroids are accidentally
withdrawn needing the patient to receive the hormone in an hexogen way, the
same as when there are extended or total thyroidectomies he must receive the thyroid hormones by
external ingestion. The GREEN SAP mechanism of action on the tumour, if this is
present, is by a mixed action, anti-angiogenic and direct citotoxic, altering
the tumour DNA bases, as it does in other kind of tumours. From this it derives
that some patients prefer not to undergo surgery but make a non conventional
medicine treatment instead, in this case GREEN SAP, achieving success,
obtaining in many cases, the tumour lisis, maintaining always a control with
thyroid biochemical profile and serial neck ultrasonographies, in order to
avoid the tumour reappearance or the metastasis that can appear in the neck or
in the distance.
Pathology:
Vulva-vaginal Carcinoma plus Solid Basal-cellular Carcinoma: Mrs. Terezinha de
Oliveira.
Name: Terezinha
de Oliveira
Age: 59 years old
Country:
Reason of Consultation:
Ulcerated skin
lesions, in nose, coccyx, right hand and right maxillary.
Personal antecedents:
Without personal antecedents to
remark.
Family Antecedents:
Without
personal antecedents of relevance.
Present disease antecedents:
She
initiates radiotherapy on
Disease evolution:
Inform of hand
sample: solid Basal-Cellular Carcinoma with deep
margin compromised. It is about a patient with skin Type 1 (Fitzpatrick
Classification) with chronic solar exposure which showed solar elastosis,
actinic melanosis, solar leuko-dermias, actinic queratosis, some basal-cellular
carcinomas. The basic treatment during this period was: solar protection,
creams based in alfa hidroxi-acids, crio-cauterization of the queratosis with
liquid nitrogen spray, surgery extirpation of the basal-cellular or subjective
lesions.
In reference to the
radiant treatment performed due to her vulva-vaginal carcinoma, it was
performed in the first place, a rescue surgery treatment and afterwards radiant
treatment practiced with photons of particle lineal accelerator in 10 MB for
total pelvis, applying the dosage of 5040 cGy in 180 cGy fractions. The
brachi-therapy of low range dosage was applied with the use of vaginal
cylinders of 2,5 cm. Of diameter. 176 -
179 – mg of 137 Cs charges, with a dosage exposure of 4793 cGy in the vagina
surface in the upper third. Treatment administered between
Rectal and
cisto-rectal mucous reaction which were medicated.
On
On
At the present is in
a real improvement, on release with a maintenance dosage of the medicament.
Conclusions:
It is about a 59
years old patient proceeding from
On
On
She begins the
treatment in June, 2001 with GREEN SAP drops and gel, on November 25th.,
2001 having the lesions disappeared.
This demonstrates us
the GREEN SAP highly beneficial action on skin carcinomas would they be of high
or low malignancy grade.
Although her
vulva-vaginal carcinoma was not treated with GREEN SAP, the medicament also plays
a preponderant role in the cure of this neoplasies.
The skin neoplasies
were cured with GREEN SAP as it was demonstrated and the patient herself let us
know so. The medicament is very useful in skin cancers, from the more indolent
to the more grave ones which can cause death. But GREEN SAP once more acted
through multiple mechanisms, achieving the cure of this patient’s skin disease,
as we have proved with many other patients.
The vulva-vaginal
cancer also could have been treated with GREEN SAP, which has an excellent
effect at this level, acting by different mechanisms that are explained in
“Conclusions on GREEN SAP action on vulva-vaginal cancer” (page 197), as well
as we have proved in numerous cases with this disease.
GREEN
SAP acts in these neoplasies by a direct effect as it has already been
mentioned and besides it has a very important role from the immune point of
view, preventing the pre-cancerous lesions of this sector of the organism.
Generally
a tumour extirpation is performed and afterwards tele-cobalto-therapy or
brachi-therapy. Many times the patients come after having the conventional
therapy done and the vascularization is not good. Therefore GREEN SAP
contributes to improve the general state, improves the appetite and the
physical activity, which allows a better quality life and a longer survival.
There are cases of patients treated only with GREEN SAP who achieve a complete
remission and clinic cure, but used after the conventional therapy its action
does not interact with the other treatments, due to its proved innocuousness
and lack of adverse interactions and disgusting collateral effects make it an
important tool and of first class in these tumours treatment. For all this it
is recommendable the use of GREEN SAP in these pathologies, with serial
controls, biochemical and ginecologic ones, and adjustment of the drops dosage
to take until the arrival to a maintenance dosage.
To
summarize, GREEN SAP acts in these neoplasies by the mechanism already exposed,
direct citotoxic action, inhibition of the neo-vascularization, increase of the
immunity, anti-infectious activity and an anabolizant action that leads to the
ground improvement and therefore of the general state.
GREEN
SAP acts on skin neoplasies by a repair mechanism of the lesion or the lesion
layer if this was extirpate. It is used orally so it acts systemically arriving
to the lesion and acting on it causing citolisis, increasing the immunity which
is impaired and provoking by immune-modulating effect an anti-neoplasic action.
The
Gel is also used concomitantly which penetrates through the skin layers in
order to act directly on the tumour focus and allowing a long-lasting skin
repair. The Gel penetrates easily the different skin layers and easily reaches
the cancerigen focus, eliminating it through the same effects as systemically,
the difference being the way through which it reaches the neoplasm. It acts on
the tumour provoking the desaferentization of the neo-vasculature disordering
the nuclear DNA, acting on its bases and by a direct citotoxic action
penetrating the tumour cellular membrane, altering the membrane potentials,
this is why GREEN SAP has a deserved place among skin carcinomas treatments,
from the more malignant to the more indolent ones, generally achieving a clinic
cure, taking into account the stage in which the tumour treatment was faced and
also taking into account the existence or not of metastasis on which it also
acts by the same mechanisms that acts on the primary tumour.
GREEN
SAP drops has demonstrated anti-tumour action, either “in vitro” and “in vivo”,
in animals and humans. Improving life quality, and by a direct effect on the
tumour. By saying improving life quality, it improves the appetite in anorexic
patients, reduces pain, helps to heal and moreover for the review of
international literature its components have a series of effects among which we
find the reducing of the tumour size what is the major objective. It improves
the immunity strengthening the patient. It has anti-bacterial activity what is
also useful in case of opportunist pathogens.
It
lacks secondary effects. It is innocuous and has no contraindications.
It
can be used with the traditional anti-neoplasic therapies without interfering
in no way with them.
The
components are safe, known and of long use in non traditional medicine, what
guarantees its quality to join and form a compound that unifies the best
properties of them all.
GREEN
SAP drops has had success in veterinary and human medicine as the cases that we
have presented guarantee.
They
are result of the observation, essay and practice of its components.
It
is expected they are part of the therapeutic arsenal to treat neoplasic
processes, in a near future, benefiting the people suffering from this disease,
which is of a multifactor origin.
The
topic use of GREEN SAP has resulted in cheloids and psoriasis, skin diseases
which practically can not be reverted with conventional therapy, is it by their
recidivisms or by not achieving to eradicate them during the first treatment.
ONCONAT
GEL has showed to be active in both diseases and its results are “a priori”
very encouraging as in many cases it achieves the cure of the mentioned
pathologies which generally do not recur with the ONCONAT GEL; making it with
surgery, liquid nitrogen, etc. (in the case of cheloids) for example.
In
our experience either in pathology and in skin the results have been very good.
Would it be combining conventional therapy with GREEN SAP or using GREEN SAP
alone in the treatment of the current pathology. This casuistic has been done
privately and we expect some time be able to introduce GREEN SAP in the
hospital background, with no doubts of the benefits this could have.
Therefore,
GREEN SAP is a new tool to fight this disease of difficult resolution, as is
cancer, which is invalidating, with expensive treatments and many times
inefficient, with disgusting collateral effects. This is why the use of this
natural therapy is hopeful to achieve a better answer to the treatment and an
upper quality of survival.
Rheumathology post-graduate
NCP 70898
Present.
I’m
sending to you my opinion about the use of our new product made of original
herb extract of our country: GOTAS GREEN SAP.
Because
of its excellent qualities I have treated different types of tumor and in
different stages of the disease, with the best results: less tumor mass, less
volume of metastases, a good tolerance to chemotherapy and radiotherapy, and
decrease the pain.
The
product is non toxic for that reason it can be indicated in adults and in
pediatric patients, showing good tolerance.
Besides
it can be taken at the same time with conventional treatments, because there is
no medicament interaction.
For
all these, I find GOTAS GREEN SAP an optimum natural alternative treatment, to
be used in oncology patients.
I
remain at your orders and receive my regards,
Dra.
Araceli Tashjian
Dermatology post-graduate
NCP 56241
With my best regards,
I am
writing to you in order to make some comments about the new anti-cancerigen
medicament based on natural extracts from autochthon herbs of our territory, GREEN
SAP Drops.
Upon the
observation of the collected data of the cases treated with this medicament,
about patients suffering from different types of cancer in different evolutive
stages, I can transmit you that they show: considering their own comments on
their subjective symptomathology, that
within a few weeks of beginning the treatment, the great majority of them
already feel relieved from their pain taking into account they need less
quantity of conventional analgesia to cope with it, with greater motility, more
energy to do their activities, with more appetite, more vitality, with a
generalized well being; and considering de objectivity of such improvements, in
a great number of cases, depending on the precocity of the beginning of the
treatment in some of them, a visualization through the battery of complementary
exams made, of a reduction of the tumor size and in some cases of their
complete disappearance.
For what,
resuming, we can tell that GREEN SAP Drops is capable of offering the oncology
patient, almost all of them, a well being and relief of the symptomathology,
which is the first goal to accomplish with the medical act in the cases where
there is no other prognosis alternative, and in the cases of earlier states
capable of a cure, a real possibility of a natural therapy, without the
secondary effects or the aggressiveness of the conventional oncology therapy
(although it can perfectly be used at the same time), which offers a new hope
for these patients.
We remain
at your order for any further question you want to ask, truly yours,
Dra. María del Carmen
García
Perú
GREEN SAP
is an extraordinary formula with which I could notice that the patients that
have begun to be administered to, immediately show fundamental signs of
improvement, I should consider that one of the aims that has to be accomplished
in the treatment of neoplasic diseases is pain control, which is unbearable,
not only for the patient, but for the family also and for the physician, with GREEN
SAP the pain subject is controlled with great velocity and effectiveness.
In precise
cases where the patient is hopeless as conventional medicine can not solve the
problem, with GREEN SAP medicament really we can not still think this way, as
the fight against the neoplasm can be initiated at any phase of this pathology;
by this I mean that I noticed that it is never too late to initiate GREEN SAP
treatment.
GREEN SAP
is a reliable formula for the treatment of any kind of Neoplasm, within the
desperation it opens the window of hope, treating neoplasies with this formula
is no more the constant deception to which many of us are used to.
Dr. Joaquín Velarde
Personally,
I do not have any final cure statistics. I do have radiographies, for example,
from the brain where a multiform glioblatoma evolution is being shown. Apart
from that I have 30 clinic reports with considerable improvements and many
others, not being patients of mine.
A
particular example was one of a woman with an uterus cancer, with liver and
bone metastasis. She had the uterus extirpated and underwent radiotherapy. She
had to quit her job because she vomited everyday and could not even swallow the
saliva. In only 3 days this woman was incorporated to her job. I still do not
have the proof of total elimination, but if proofs value, I have all the
world’s ones.
Supposing
that a placebo could act this way, then I would use placebo, because it allowed
me to offer the cancer patients a comfortable life.
Anyway I
refer them to
I say
good-bye, not without telling you that the suggestion can be maintained for
sometime, not forever, and if 3 or 4 months that my patients have of treatment,
have allowed them a breath-take in reference to sleep, pain. Summarizing, life
quality, these products, only just for that have validity.
A hug,
Dr. Miguel
Aristy
Internist
physician and Neurologist
A cordial
hug.
In
reference to my observations on GREEN SAP Drops, they can be resumed as
follows: I have seen that the less they produce is a life quality improvement
in the cancer patients. When they are definitively terminals, they help a lot
they can make their final step in peace and without pain. In some of them the
improvement starts in a few days, increasing the appetite and reducing the
pain, sometimes in an admirable way. In some others, I have seen the detention
of the tumour growth and the process stays “frozen”… Summarizing I could say
that it is a therapeutic element very important that acting in an unspecific
way on the immune system achieves to improve the life quality of the cancer
patient, increasing his survival, relieving his annoyances associated to his
kind of tumour, stopping the tumour growth. It is also very notorious its
protective action against the side effects of the radiation and chemotherapy. I
believe that within a biological scheme of facing the cancer patient, GREEN SAP
Drops must occupy an important place due to its clear anti-tumour action and
because of the lack of secondary effects.
Carlos Eduardo Medina Arenas M.D.
From: diskcarimbos@terra.com.br
Sent:
I would
like to inform you (Mr. Pacheco) had some tumours (melanoma) in the brain. One
of them was of 1,8 cm. and others small. From the point of view of the doctors
that treat my father, he had 3 months maximum of life. But anyway my father had
from 25 to 30 radiotherapy sessions done in his brain and before that had a
chemotherapy session. My father begun the radiotherapy and at the same time the
use of GREEN SAP Drops. We are in October and 3 to 4 months have already passed
since the beginning of this treatment. We performed a battery of exams,
tommography, radiography, blood exam and many others, it was demonstrated that
my father does not have any tumour in any other part of the body, but only in
his brain, and that this biggest brain tumour did not grow, that is, my
father’s disease is stabilized. He has great weakness in his leGREEN SAP and
already had thrombosis, but it is under control. He does not feel headaches,
and we are hopeful that this tumour would have stopped growing, as from the
doctors’ point of view if it was growing, my father would not have had more
than 3 months of life. This is more or less my father’s clinic situation. I ask
you to send me some answer so that we can go on with the treatment which has
never stopped. I am grateful!
Data:
Saturday, April 28th., 2001
PATIENT’S
DATA
Name: Mirna
Surname:
Galarza
Contact:
Son
Contact’s
name: Daniel
City:
Reconquista
Country:
Telephone:
03482-421200
Address:
San Martín 1456
Clinic
story: She started with anaemia. The cause was looked for without results. She
had done: Ultrasonography- serial radiography- Blood exams- Proteinogramme-
Colon-enema (diverticulas and some polyp were found). The only thing that
continues abnormal is the eritrosedimentation value (it reached 100 mm/h). (can
be due to the osteoporosis? or due to a rheuma or arthrosis process?. She does
not feel any annoyance except for the joint pains, she did not loose any
weight.
Clinic
Diagnosis: By now and by phone, osteoporosis.
Anatomy-pathology
Diagnosis:
Surgery: No
Kind of
surgery:
Chemotherapy:
No
Scheme:
Radiotherapy:
No
Dosage:
Tolerance
to medicaments: Good
From: Hugo
Daniel Montyn
Sent:
Claudio,
how are you, the new order to purchase 5 bottles is already done. I tell you my
mother is doing a normal life with very little joint pain and she will be
beginning the 15 daily drops intake. I hope the delivery will be fast as she
has only one bottle left. Thank you very much.
Daniel
Reconquista.
From:
Daniela Eguiazabal
Sent:
Subject:
Elsa Julia Frattesi
My mother
is 61 years old and she has Parkinson since 15 years ago. Three years ago she
was diagnosed bone-necrosis in her right knee which has left her almost unable
to move by her own means. At the beginning of the year she started with genital
haemorrhages (as if she was menstruating) and a fibroma was detected, they
began treating her to stop the haemorrhages but after a couple of months they
repeated again that was why they decided to perform a biopsy to analyse the
causes. Dr. Copolecchia (ginecologist) was in charge of practising the biopsy
and it was him who detected the uterus horn lesion. After confirming the diagnosis
with the pathology results he contacted us with Dra. Brosio (oncologist) who
told us that the lesion’s grade of advance avoided they could make a surgery
and extirpate the damaged part and that the treatment we should follow by now
was radiotherapy. This new situation caused us a lot of affliction and we
started to look for alternative solutions and there was how marvellous comments
about the drops reached us. We consulted the web site and are very anxious to
begin the treatment with the drops as we trust they will be able to help us to
overcome this new challenge life gives us.
Well, we
are looking forward to hearing from you soon.
HuGREEN SAP.
Elsa,
Daniela and Pamela.
From:
Daniela Eguiazabal
Sent:
First of
all we would like to thank you for your soon reply, as we are really very
interested in our mum beginning as soon as possible with this treatment.
Tomorrow we
will have the computerized tomography result and the thorax and pelvis
radiography which she had done last week, but we can advance you some dta of
her general state.
She takes
her Parkinson medication every three hours, but sadly as she is in the limit
dosage, the druGREEN SAP are not sufficient to maintain the improvement until
next dose. When the medication is “low” her general situation is characterized
by very intense muscle pains, loss of muscular tone, stiffness, slow movements
and anguish states and reluctance which oblige her to stay laid down until next
dose makes effect. While the medication is “high”, although she keeps on having
motility problems, she is able to develop her daily routine in a better way and
her spirit tends to improve.
At the
present moment she is overweight, but the last clinic exams (urine, blood,
blood pressure, etc.) show results within normal parameters. It must be
mentioned that within her diet it is not recommended protein intake, at least
during the day, as it blocks druGREEN SAP effect; additionally she does not
present difficulties in the ingestion of any kind of food, although she must
control quantities as she has a hiatus hernia, which causes her reflux when she
feels too plenty. She has some intestinal troubles, that is why every night she
takes a digestive herbal tea and a spoonful of Vaseline, which lets her
regulate the situation.
Her spirit
suffer from some ups and down, but she is supported by her family and the
psychiatrist who sees her for more than 2 years now, that is why observing her
we notice she is confronting this situation quite well.
We hope
this information would be useful to you to define mum’s treatment, and as soon
as we have the previously mentioned studies’ results, we will be in touch with
you.
We ask you
please to let us know if we already are in conditions to start the treatment or
it is necessary to send you more information. If we are in conditions to start,
please let us know the drops’ cost and the fastest way to access them.
We say
good-bye and thank you for the aid you are giving to us.
Elsa,
Pamela and Daniela
From:
Daniela Eguiazabal
Sent:
Subject:
Medicament’s delivery
Hi, we just
wanted to inform you that we received without any kind of problem the drops and
mum has already begun with the treatment following the instructions you sent us
by mail. As it was to be supposed, some doubts aroused which we hope you will
be able to answer us.
1)
How
do we have to store the bottles that are not being used?
2)
Can
she take the drops with her Parkinson medication?
3)
Is
it necessary that half an hour after taking the drops she eats anything?
Well, these
are the inquiries that aroused by the moment, we say good-bye and we hope we
will be able to send good news soon.
HuGREEN SAP.
Pamela and
Daniela.
From:
Daniela Eguiazabal
Sent:
Subject:
Good news from Elsa Frattesi
Hi to
everybody,
It’s us
again to tell you that luckily mum already finished the ray applications and
the studies showed that the tumour has reduced and become fibrosed. There are
also good news about her bladder, luckily it is not damaged and it was possible
to retire the catheter she used since 5 months ago.
Luckily the
clinic general situation is very good as well as her spirit and the doctors are
very happy with the obtained results.
For all
this we would like you please to tell us how do we have to follow the drops
treatment, do we have to administrate the drops the same way (4 times per day
45 drops)? Until when does she have to take the drops?
This Friday
my mum is travelling to the coast to enjoy some deserved holidays in the beach
and if you consider it is necessary for her to go on with the treatment we
would need you to prepare urgently for
us six bottles which will be taken from your office in
Well, we
kindly say good-bye and hope you can answer us as soon as possible.
Pamela and
Daniela Eguiazabal.
From:
Delaigue, Hernan HM
Sent:
Subject:
Delivery confirmation
Mr. A Manuel,
Hi, well as
you mentioned in the attached e-mail, I have not heard of the medicament’s mail
until this morning, so as to withdraw it from my city’s mail box.
So once in
my hands I will let you know.
Have a
merry Christmas and a happy new year.
Hernán
Delaigue R.
From:
gotitas.com
Sent:
To: Delaigue.Hernan.HM@bhp.com
Dear Mr.
Hernán Delaigue,
Due to the
absence of mails from you, we are worried about the arrival of the medicament
up to your home, as we are in a more than prudential time for this delivery to
be in your hands, in case it has not arrived, we ask you please to communicate
with the customs or with your country’s accelerate mail system. As soon as you
have some news please let us know so that we can download in our registers such
information, also if it is already in your hands.
We are
sending you a big hug from
For
gotitas.com
From:
Delaigue, Hernan HM
Sent:
Subject:
Cheloid treatment
Sirs,
I am
writing to you in order to tell you that the cheloid treatment recommended by
you applying the drops, was totally eliminated, only remaining a scar. The
cheloid my son had behind his ear produced by a surgery had produced itchiness,
inflammation and an always irritated area.
This is why
I thank you for the attention and recommendations when I asked for them.
I hope you
have had a merry Christmas and wishing you all the best for this new year, and
hope you can reach many other persons who need an improvement.
Sincerely
yours,
Hernán
Delaigue R.
From: Hugo
Ramon Ruiz Fleitas
Sent:
Dr. Bernardo Udaquiola,
Mauricio Ruiz’s case
I thank you
for your attention of immediate answer to my e-mail, but I would like to make
some corrections of some mistakes made in the writing of the previous one and
are referred to:
All the
content is correct except for the indication of the brain side in which the
tumour was situated in each case as I exposed in the previous e-mail.
I beg you
notify me of this mail reception. I will be expecting any need of explanation
and we expect with interest your recommendations and the possibility of the use
of GREEN SAP.
GreetinGREEN
SAP.
Hugo Ruiz
From: Hugo
Ramon Ruiz Fleitas
Sent:
Subject:
Mauricio Ruiz’s case
Dra.
Araceli Tashjian Ramirez,
Allow me to
thank you from now on the interest in answering my consultations referring to
my son Mauricio’s case. Due to some mistakes made in the first e-mail sent, I
rectified them through another one I sent on Saturday 22nd. of the
current month. To be more clear about it, I consult you:
Kindly
yours,
Hugo R.
Ruiz Fleitas
From: Hugo
Ramon Ruiz Fleitas
Sent:
Subject:
Mauricio Ruiz’s case (2)
Dra. M. del
C. García,
Thankful
for the soon reply to my requests and helping for a better acknowledge of the
referred patient I inform you that Mauricio has at this moment 34 k. and is
recovering from the oedema that surrounds the tumour which was target of
radio-surgery on March 25, of the current year. It causes him headaches he is
being treated with corticoid (2 mg every 6 hours) and now and then he throws
up.
We are
awaiting for his MR periodic controls to decide eventually a surgery to
extirpate the tumour in necrosis process; if the patient does not react to the
treatment previously mentioned.
I will keep
you informed. I expect your comments.
GreetinGREEN
SAP.
Hugo Ruiz.
From: Hugo
Ramon Ruiz Fleitas
Sent:
Subject:
Mauricio Ruiz’s case (3)
Dra. M. del C. García,
I repeat my
thankfulness for the deference of soon reply to my consults. Following the
first instructions received in the previous e-mail and as I commented, thank to
the availability from another patient of yours who have in
Hugo Ruiz.
From: Hugo
Ramon Ruiz Fleitas
Sent:
Subject:
Mauricio Ruiz’s case. Evolution
Dra. M. del C. García,
We have
received your e-mail and will be waiting the arrival of your “drops” delivery.
In
reference to Mauricio’s evolution, as I previously informed you he underwent on
March 25th., 2002 a radio-surgery and from the end of May he
suffered from strong headaches. He was hospitalised from May, 31st.
to June, 12th., afterwards from June, 25th., we started
using the “drops”, following received instructions, but was interrupted from
the 29th. of the same month due to an intensification of the
headaches, he had very strong vomits and
was hospitalised from June, 30th. to July, 5th.,
being strong medicated based in corticoid. For all this we have effectively and
uninterruptedly administrated the “drops” to him from July, 2nd.
Mauricio had a magnetic resonance control done on July, 19th., and
the doctor’s comment says: “ it is observed a reduction in the peri-lesional
oedema and a reduction in the administrated contrast’s capture”.
I can tell
you that the patient is in very good mood, good appetite, with no headaches
since we came out from hospital, but with lots of cares so as not to expose him
to eventual infections, due to his corticoid based treatment, which would
reduce his defences (as for the doctor’s expression). With this comments, we
understand that the administrations of the “drops” are contributing to his good
recover and we expect your indications to go on with the treatment. GreetinGREEN
SAP.
Hugo Ruiz.
From: Hugo
Ramon Ruiz Fleitas
Sent:
Subject:
Drops arrival
Dra. M. del
C. García,
I thank you
for the soon reply to our request of bottles of “drops”. Certainly, today at
Hugo Ruiz.
From: Hugo
Ramon Ruiz Fleitas
Sent:
Dearest
Dra. Ma.
I
appreciate your interest referring to Mauricio’s evolution as well as the
information about the GREEN SAP
Certainly
on August 27th. Mauricio had a new MR exam, and afterwards we were
informed that the “brain oedema” has reduced significantly what led to determine
to reduce his “corticoid” dosage (which he received in a maximum dosage) in
order to retiring it totally but slowly. Referring to the tumour it presents a
slight improvement, with reduction of the contrast impression in its borders.
We expect this is part of a process in order to the disappearance. His next
control will be done at the end of October.
He is
receiving the drops in the previously indicated dosage and evidently he
tolerates it very well, with no adverse reaction. His spirit is good, with great
vitality, with normal activity. He is clinically stable, with no disturbance.
I would
like to consult you the following: I consider important that you could see the
MR images we have been performing (for example the 3 or 4 last ones), so as to
have a clear idea of the lesion’s evolution. This is why I could send you by
courier the radiographies, but we would have to have them back to continue the
controls. In case you want so, to which address I should send them? And how
much would be the cost of re-sending of the radiographies? I repeat my thanks
for the interest manifested and awaiting your comments, I say good-bye.
Hugo Ruiz.
From: Hugo
Ramon Ruiz Fleitas
Sent:
Subject:
Previous e-mail complement
Appreciated Dra. Ma. del
C. García,
Complementing
my e-mail referring to Mauricio’s evolution, I transcribe as follows Dr.
Antico’s comments referring to Mauricio’s evolution through the MR images.
GreetinGREEN SAP.
Hugo Ruiz.
From:
Antico Julio
Dear Mr.
Ruiz,
I received
Mauricio’s studies, observing in the images a reduction of the peri-lesional
oedema and of the lesion’s mass effect which produces a smaller deviation of
the middle line structures. Referring to the tumour itself, there is a slight
reduction of the contrast’s capture in its borders. Resuming I believe that
there is a slight improvement in the evolution and that confirms my decision of
progressive reduction of the corticoid until its complete retire.
I beg you
to maintain me informed of the evolution. I consider a new MR control in two months time.
Sincerely
yours,
Dr. Julio
Antico
Neuro-surgery
Radio-surgery
chief
Leksell
Gamma Knife FLENI
Montañeses
2325 (1428)
Buenos Aires – Argentina
TE: +5411 5777-3200 intern 2931
E-mail: jantico@fleni.org.ar
From: Hugo Ramon Ruiz Fleitas
Sent:
Subject:
Comments on Mauricio
Attention:
Araceli Tashjian
Appreciated
Dra. Araceli,
I
appreciate the attention from “drops” getting interested in Mauricio’s state of
health. He is in good state with normal activity enjoying the school holidays.
In the next days we will be asking for the “drops” delivery.
I express
in my family’s name our sincere wishes of a merry Christmas and a better year
2003, to you and all the Drops’ staff. GreetinGREEN SAP.
Hugo Ruiz
F.
From: Hugo
Ramon Ruiz Fleitas
Sent:
Subject:
Comments on Mauricio’s health
Mr. Drops,
I want to
comment you that Mauricio is following as always his treatment with GREEN SAP
Drops, at the indicated dosage. However I must comment you that in a recent
image control study (
In the next
days we will be asking for a new deliver of GREEN SAP Drops.
GreetinGREEN
SAP. Thanks.
Hugo Ruiz.
From: Hugo
Ramon Ruiz Fleitas
Sent:
Subject:
Comments on Mauricio’s health – Anatomy Pathology
Mr. Drops,
Attention:
Dra. Araceli Tashjian
Answering
to your e-mail I transcribe you part of the anatomy-pathology inform
corresponding to Mauricio’s extirpated tumour on March, 7th. of the
current month, which says:
“… we would
tend to ..re-classify this tumour according to this more recent evidence as of
grade 2 or cellular…”, according to the most recent publications (which
classify them in: of non atypical usual histology or grade 1, cellular or grade
2 and anaplasic or grade 3).
Reference:
OD Wiestler and M. Rosenblum. Ependimoma. In WHO Classification of tumours.
Blue Book. IARC, Lyon, 2000.
Yours,
Hugo Ruiz.
From: Jorge
Lindh
Sent:
Subject:
Drops prepared
Dear Sirs,
My name is
Jorge Lindh, Argentinean living in
In July,
1998 I underwent a surgery in which I was extirpated the left kidney, cancer
damaged. Such cancer resulted after the analysis performed, to be (translated
from Swedish) “light cells adeno-carcinoma”. It was believed at the beginning
that the cancer had been definitively eliminated. A year later – after two
controls which did not show any anomaly -
in July, 2001, shortly after the control was done, I was appointed at
the hospital to have an additional thorax tomography done. In that occasion
they discovered metastasis out of both lunGREEN SAP – according to my hospital
record, lymphatic metastasis in left and right lung that compress both the
trachea and the oesophagus. Later on it an additional metastasis in a vein was
discovered in the area of the extirpated left kidney and one behind right
clavicle.
This is my
present situation. Throughout my sister who lives in
I travelled
from
I will call
you tomorrow, Tuesday.
I will be
looking forward to hearing from you, sincerely yours,
Jorge Lindh e-mail: jorgelind@hotmail.com or sueca@sinectis.com.ar
From: Jorge
Lindh
Sent:
Dear
Leonel,
After
something more than two months that we have met in
From my
point of view, I can tell you that I’ve feeling better since I begun with the
drops. The annoyance I had to swallow due to the metastasis in both lunGREEN
SAP compressed the oesophagus and trachea, has disappeared. Now I swallow as if
there was no any “obstruction” blocking the food passage. This is a subjective
appreciation. We will see the truth with next 6 day’s proves.
On the
other hand, it was nice to receive a mail from a “disgraced mate”, I’m
referring to Mr. Jorge Suarez who also is treating himself with the drops. It
seems to me it is very useful to create a kind of users net to exchange
experiences. Jorge’s contact was a right initiative from you.
Another
favour, please tell about this mail to Dr. Harriague, as I promised him to keep
in touch.
A big hug
and thanks from now for your help.
Jorge Lindh
From: Jorge
Lindh
Sent:
Hello
Gladys,
I apologize
for the delay but I was away for a few days. Last Monday I received the results
of the exams I had been done.
A hug for you all.
Jorge Lindh
From: Jorge Lindh
Sent:
Subject: confirm consultation
Dear Gladys,
Thanks for your reply. I confirm I will be with
you on Thursday at 15 hours. At the same address than last time, in Pocitos?
Thankful for your help.
Sincerely yours,
Jorge Lindh
From: RENILUR S.A.
Very dearest Mr. Jorge Lindh:
On Thursday 14th. of the current
month at 14 or 15 hours is what I could arrange with Dr. Harriague.
What time do you arrive? Confirm us which is
the more convenient.
GreetinGREEN SAP.
For gotitas.com
Gladys Gómez
From: Jorge Lindh
Sent:
Subject: News
Mr. Leonel,
Just yesterday I received the results of the
tomography and tests in general.
From our last meeting in March six months have
passed without any problems or major annoyances. The dosages have been
respected religiously and I think that the treatment has resulted by the
following:
In my yesterday interview with the doctor I was
informed that the abdominal metastasis has totally stopped growing. The same
occurred with the ones at the right clavicle, it totally stopped growing.
(since last February tomography). In reference to the both lung metastasis,
which compressed the trachea and oesophagus, he told me they were collapsed,
that they were left without “food” and have been reduced. I did not say
anything and the doctor by himself asked me if I went on “taking those pills or
whatever I brought from
Leonel, a big hug for you all – with the good
news – and I hope to see you soon (I estimate towards the end of September).
GreetinGREEN SAP to you all.
Jorge
From: Jose Medina
Sent:
Subject: Good News
Hi! I write to you to tell you how my father
was doing. To refresh your memory, he was diagnosed in Puerto Rico Right lung
cancer type 4 with liver and adrenal metastasis. He went to
We are hopeful that the drops have achieved some
way or the other my father’s recover and therefore we are very grateful. We
will soon make the next order as he is running of them. I would like to know
which would be the amount of drops that have to be taken in this situation. I
will thank your reply.
I wish to tell you that I referred your drops
at
Go on saving lives as you did with my father’s.
GreetinGREEN SAP from
Mayrin Sanchez
From: Hernan
Sent:
Subject: Information
I have a relative of mine with lung cancer, I
was visiting your web site in Internet and I would like to know if the prices
of the products that appear there (for example GREEN SAP Drops 50 ml) are still
the same. I live in
I am looking forward to hearing from you soon.
Kindly yours,
Hernán Mena.
From: Hernan
Sent:
Subject: Complementary information.
Hello! Just today’s afternoon we were able to
contact your medicament. There was a mistake in the address, maybe when the
transport or the package was done, but luckily after some “come and go” it
arrived at its original address.
I have some questions to ask that are not very
clear for me, when I visit Internet and consult the drops’ dosage.
We think
that after resolving these inquiries, my father would agree to begin the
treatment correctly and for the period of the time the disease requires.
Kindly
yours,
Hernan Mena
From:
Hernan
Sent:
Subject:
Information
Hello!
According
to the last e-mail received, I would need to make a request for 3 (Three) more
50 ml. Bottles. I would like to know if there are any changes in the product’s
prices and to know to whom the deposit by
From now,
thank you very much and I await for your soon reply.
GreetinGREEN
SAP.
Hernan
Mena.
From:
Hernan
Sent:
Subject:
Re: News
First of
all, thank you for being concerned about my father’s health. At this moment I
am at Carlos Paz city, Cordoba province, due to work, but I understand thinGREEN
SAP are going quite well, every treatment was finished, being it drops,
chemotherapy and radiotherapy, so there would be a new study to perform and
compare the results with the previous ones. Any news that could emerge from
this, I would make you know immediately… Thanks again…
Hernan
Mena.
From:
Hernan
Sent:
Subject:
Bad news
Sirs from
Drops.com,
In August,
2001, I contacted you in order to receive information about your product, since
I had my father with lung cancer. Well, I hope this short introduction can
situate you in the case.
The
treatment, at that moment, was made strictly, as apart from the Drops, the
medical treatment was never quitted (chemotherapy and radiotherapy),
complementing it with the famous “gorgojos” and a strict diet too.
Now, a week
ago, new analyses were performed, and in a head tomography a new inconvenient
arouses: according to the doctor, there is a “Brain Dissemination”, that is, as
for the very little I understand the subject, it is about the left part of the
brain’s inflammation, that manifests in partial and temporal memory loss, apart
from the motor problems in upper and lower joints.
Also
according to the doctor, this problem is maybe more grave than the previous
one, as, quoting, he said to us“ it is the beginning of the end”…
All this
previous description has only one reason: consult you if there are any chances
to make a new treatment with the Drops. In the Internet web site does not
appear any case similar to this one, this is why I am writing to you again so
as to please inform me.
From now,
all my family and I are deeply thankful…
Hernán
Mena.
From:
Hernán Mena
Sent:
Subject:
Inform and consultation
Dear Sirs
from Drops,
Next I
transcribe you two informs of the evolutive process of my father’s disease,
with its respective dates.
Inform:
Encephalic CAT
Date:
The
encephala was studied by axial and sequential tomographic cuts parallel to the
meatal orbital line. The study was reinforced by 1 cc/kg weight endo-venous
contrast administration.
Small
hypo-dense images represent oedema.
This oedema
regions supra and infra tentorial are generated by neo-formed elements, which
stand out after administrating the iodated reinforcement.
There are
two small lesions in posterior fosse, one in the left cerebella’s hemisphere
and the other one in the cerebella’s vermis (slice 02 with contrast). In the
supra-tentorial level there is a big lesion in the left temporal lobe and
others in the left occipital area, right optical thalamus, left lateral
frontal, middle supra-ventricular parietal, right middle supra-ventricular
parietal and left polar frontal.
Resuming:
Multiple secondary lesions.
Inform:
Cranial C.A.T.
Date:
Procedure:
Cranial
C.A.T. was performed, making axial cuts of 5x10 mm thickness consecutive
intervals of 5 and 8 mm parallel to the orbito-meatal line and
post-administration of hydro-soluble tri-iodated E.V. contrast substance.
Interpretation:
Present
C.A.T. was compared to previous C.A.T. brought by the patient observing more
than 50% reduction of the visualized lesions in left frontal, left occipital
and left cerebella’s hemispheric and cerebella’s vermis areas.
The rest of
the lesions are not visualized in this opportunity but there is a hyper-dense
area of 7 mm diameter in right frontal sub-cortical area, not observed in the
previous study, with no signs of oedema. Dot-form images of calcium density are
observed, left para-ventricular, not observed in previous C.A.T., in some cases
it can be due to post-treatment densitometric change.
Conclusion:
Marked
reduction (more than 50 %) of the visualized lesions in left frontal, left
cerebella’s hemispheric, cerebella vermis and left occipital areas. In this
opportunity dot-form lesions are visualized, calcium, left para-ventricular,
not observed in previous C.A.T., and an hyper-dense area without oedema, not
typically proliferative, right frontal sub-cortical, repair lesions? Incipient
secondary lesions?
In
reference to the textual transcribed informs, the fundamental consult is if he
has to go on with the present treatment (60 drops – 4 times per day) or if he
has to make any dose changes. Besides we would like to know if he has to go on
with the strict diet that is recommended on the web site or he can slowly
incorporate some up to now “forbidden” food and/or drink.
From now,
all my family’s members infinitely thank you for the interest and cooperation
offered in this case and we are sure that my father’s quality of life has
depended and depends not only on our faith and hope, but also on your valuable
help. THANK YOU VERY MUCH.
I am
looking forward to hearing from you soon, kindly yours,
Hernán
Mena.
From:
Hernán Mena
Sent:
Subject:
Information
Sirs from
Drops,
Having
consulted with my family your proposal of having my fathers’ disease case
appearing in your web site, I communicate you that we do not have any kind of
trouble in doing so.
By the way,
I inform you the change in my e-mail address. The new address is:
I again say
to you in my family’s and myself name, THANK YOU VERY MUCH.
Hernán
Mena.
From:
Ricardo Abraham Topalian Doganian
Sent:
Subject:
Ricardo from
Dear
Leonel,
I am
“bothering” you again with questions. I would like to know from you if it is
primordial for me to send you the magnetic resonance my mother had done in the
end of August, if it good for the doctor to see it, because I found a place
where scan those thinGREEN SAP (radiographies and so on) and they themselves
send them by Internet. If your answer is yes, I’ll be sending it on that same
day. Another question I would like to ask is: 1) Do I go on with the prescribed
dose: 45 drops, 4 times per day? 2) I want you to have the time schedule of the
medicaments she takes in order to know if there is any interference between the
drops and the medicaments the doctor indicated her:
Do you
think the schedule is fine or should I change anything?
Leonel,
thanks for everything and I await for your reply. A hug,
Ricardo
Topalian
Dear
Leonel,
Since my
last message I did not contact you again, receive my apology. I couldn’t get a
place where I could scan the exams and send them to you, but from that day
until now my mother had 3 (three) cranial magnetic resonances performed and
luckily the cancer has not returned. The last one was last April, 27th.
and nothing appeared, in the laboratory’s opinion: “in reference to previous
exam of
Ricardo
Topalián
Dear
Leonel,
Thank you
for answering me so soon. I will do whatever it takes to send you the exams. I
would only like to ask if the 40 morning drops must be given at 4 in the
morning or at 10 in the morning, keeping the fast period 2 hours before and 2
hours after the drops. A hug,
Ricardo A.
Topalián
From:
Ricardo Abraham Topalian Doganian
Sent:
Subject:
Answer medical staff
Br.
Cristina Eliópulo,
Thanks for
answering me so soon, I will keep you informed on the subject and of course you
can give my e-mail to that couple. Sincerely yours,
Ricardo A.
Topalián
P.S.:
please, don’t treat me as an old man, I’m not so old.
From:
Ricardo Abraham Topalian Doganian
Sent:
Subject:
Ricardo from
Dearest
friends,
I am
getting in touch with you at this opportunity in order to clear out one doubt.
My mother is taking the drops since August, 2000 and luckily the cancer has not
manifested again, and, unluckily, it seems like my mother-in-law has presented
some trouble in her liver and the doctor sent her to an oncologist because it
can be a tumour. She has to make some exams yet and afterwards has to go to see
the oncologist so as to know what she has and we would like to know if in case
it was the same she could take the drops for that kind of cancer. When I have
more information I send you another message.
I already
thank you for your reply,
Ricardo A. Topalián
From: Ricardo Abraham Topalian Doganian
Sent:
Subject:
Ricardo from
Dear Dr. M.
del C. García,
I’m getting
in touch with you again in order to inform you that my mother had a magnetic
resonance done in August (she has to have one every six months for control),
and the result could not be better: there is no evident alteration comparing to
the previous exam.
Kindly
yours,
Ricardo A.
Topalián
From: Hilda
Smith Vivas
Sent:
Subject:
Information required
I’m a Cuban
doctor and my father presents a prostate carcinoma in an advanced stage. I am
working in
I’m looking
forward to hearing from you soon, kindly yours,
Dra. Hilda
Smith Vivas.
From: Hilda
Smith Vivas
Sent:
Subject:
Thanks for the information
First of
all my greatest greetinGREEN SAP for the attention you gave me as I am in a
desperate situation with my father’s problem.
I have
great interest that my father receives the medicament, that’s why I need to
know the ways of payment for it.
I am
working on my own in
With the
new migratory laws for Cuban doctors currant from last September it is
forbidden to me to return to my country, I only knew about my father’s disease
in December and I am desperate to see him again and to have him recovered.
My e-mail
in
I need to
know the ways to make a bank transference, agency name and data, account
number, etc.
Our address
in
Kelly Santos Smith
Edificio E 51, apto. 21, zona 11. Alamar. Habana City. Cuba.
I immensely
thank all of you for this hope of life you give me and desire you the best
successes of all the world.
In Cuba I
worked as Radiologist in the Oncology National Institute but as for merely
economic reasons I went out of the country, now it is forbidden to me to come
even to visit due to my father’s disease and you have returned hope to me for a
longer survival and, most important of all, a useful life, without suffer.
I forwarded
the message I received to my daughter and son-in-law, so they will be updated
of the situation.
I repeat my
thanks for your solidarity an comprehension and I anxiously await the
transference data.
Lots of
greetinGREEN SAP and my best wishes for you all. Thank you very much and God
bless you all.
I await
your reply,
Dra. Hilda
Smith Vivas.
From: Hilda
Smith Vivas
Sent:
Subject:
New explanation
First of
all my kind greetinGREEN SAP to you all.
I need to
know urgently if the drops have expiration time, because I’m interested in
making a purchase to guarantee at least 1 year of treatment.
I came to
know today that there have been some problems with the relation between
If it is
possible to buy a year’s supply, please send me the answer urgently in order to
make the transference, as well as the cost including all the taxes.
I apologize
for my despair, but I am worse every day, frightened of anything that can
happen, I also wanted to tell you that if the state doesn’t allow the
medicament entrance to Cuba, please let me know so then I would receive it here
in Luanda, Angola and would make it arrive by other means.
I apologize
for my anxiety, but I repeat, I am frightened that any problem could emerge. I
repeat my thanks for to excellent comprehension and help.
My best
wishes for you all.
Most kindly
and with love, awaiting for your reply,
Dra. Hilda
Smith.
From: Hilda
Smith Vivas
Sent:
Subject:
Dra. Hilda
First of
all my greetinGREEN SAP for you all and thanks for the soon and excellent
attention you gave to me.
Yesterday,
more calmly, I checked with other colleagues your web site and I found a
testimony of an old lady with bone-muscle-joint pains she was successful to
solve with the product.
My mother
suffers intensely from those pains, she is 83 years old, she has hypertension
and an important cardiac insufficiency, osteoporosis and a monostotic Paget in
L5. She is suffering too much pain in her body and I don’t know what to do.
I beg you
to tell me if she can use the GREEN SAP treatment and how, as if it is possible
I would like to buy it for her too.
I’m very
thankful and awaiting your indications, kindly yours,
Dra. Hilda
Smith Vivas.
From: Hilda
Smith Vivas
Sent:
Subject:
Dra. Hilda Smith Vivas.
My greetinGREEN
SAP for you all and my wishes of a good health and prosperity although the
situation going on. The present mail is to inform you that my father has had a
new PSA done with figures of 11.87. The previous exam was situated in 88.
The bone
survey revealed generalized arthrosic changes and increased bone density in the
lumbar segment of the vertebral spine. We will keep you informed of his
evolution as well as my mother’s. Kindly yours,
Dra. Hilda.
From: Hilda
Smith Vivas
Sent:
Subject:
Dra. Hilda Smith Vivas.
My greetinGREEN
SAP fro you all and thanks for the quick attention.
As soon as
I am informed of next ultrasonography’s result, we will send you the result.
With great
love to you all, my cordial greetinGREEN SAP,
Hilda.
From: Hilda
Smith Vivas
Sent:
Subject:
Dra. Hilda Smith Vivas.
My greetinGREEN
SAP and wishes of good health and success.
My father
had a trans-rectal ultrasonography done and the prostate has a volume of 50
cc., with reduce in its ecogenicity in its peripheral portion, which is
thickened.
They
recommended a new biopsy.
The PSA was
situated a few days ago in 11,87.
He has
already accomplished the 4 months with the dosage of 60 drops 4 times per day,
he goes on with the acidity and presents two daily diarrheic depositions.
My mother
hasn’t resolved her joint pains with the treatment, so she suspended it as you
had recommended me, but it came to be that she is an habitual constipated and
has a functional mega-colon, she tells me she had restarted taking them,
because while she was using them, she could defecate daily and with no effort,
she suffers from constipation up to 10 days without defecating.
I don’t
know if you already had this data that it is useful in chronic constipation.
I’m looking
forward to your orientations about my father, kindly yours,
Hilda.
From: Hilda
Smith Vivas
Sent:
Subject:
GreetinGREEN SAP from Dra. Hilda
First of
all my greatest greetinGREEN SAP and thankfulness for your concerns about my
father’s situation, which is quite fine.
I didn’t
write to you before, because we don’t have the P.S.A.’s result yet, performed
after the radiotherapy.
As I
informed you, he was indicated 30 radiotherapy sessions which ended on day 9 of
the current month, they immediately performed a new P.S.A., last one was in
8,11 but we will have to wait until several patients are in the row to have it
done due to difficulties with the reactives.
His
physical situation is quite good, he feels fine although he presents an
increased polaquiuria, apparently a radiotherapy sequel, which had to be
interrupted 2 weeks because he suffered from some burnts.
The pains
he previously presented, specially in the lumbar region and right hip, have y
reduced markedly, the appetite is increasing and he goes on with the drops
treatment, as you recommended us.
As soon as
I have got some news, I will inform you.
Thanks for
your attention.
Kindly
yours,
Hilda.
From: Hilda
Smith Vivas
Sent:
Subject:
Dra. Hilda Smith Vivas
My greetinGREEN
SAP for you all.
I will tell
you I’m very happy and thankful to you because my father was declared
clinically cured.
He had the
Androcur suspended for 2 months and was indicated to have a new PSA done, the
last one after the radiotherapy was of 7,2 still high, but they associate it
with the radiant treatment, that is why they recommended him to repeat it after
2 months.
He goes on
with the drops treatment 40 drops, 3 times per day.
I wish to
know what do you recommend me to do in reference to the treatment.
Kindly
yours,
Dra. Hilda.
From: Hilda
Smith Vivas
Sent:
Subject:
From Dra. Hilda Smith.
Subject:
Clinic record resume
Francisco
Raul Smith Belgrave
Male
patient of 77 years old with mesenteric thrombosis antecedent in January, 1995
he underwent surgery and is evolutioning without difficulty. In December of
last year he started with night urine and weak urine flow reason why he was
attended by an Urologist who observed by rectal digital examen an increased in
size and hardened prostate of woody consistence due to what he indicated the
following complementary exams which showed the following results:
Hemoglobine 134 g/l
Eritro 14 mm/h
Creatinine 98 mmol/l
Prostate U/S Almost empty bladder, nevertheless increased in size
prostate globally and heterogeneous, which measures 55/41/41
Upper
hemi-abdomen U/S Fatty liver, no
nodular lesion, no other alterations
Bone gamma-graphy Nuclear bone scan where an
increased RF accumulation is observed in lumbar vertebral spine (L5) and
reducing of it in both sacroiliac joints.
Prostate biopsy:
PSA 88.1
ng/l
It is
concluded that the patient presents a moderately differentiated prostate adenocarcinoma no metastasic and was
indicated to start with Androcur 2 daily tablets. A month after having begun
the treatment the PSA is repeated
Besides the
patient experiments a remarkably improvement in reference to the night urine
previously mentioned.
It wasn’t
possible to follow up through a PSA as there are no reactives in the country
but the imagenologic study was repeated on
Now the
patient only refers to present pain in the hip joint.
On
He goes on
with the drops treatment at a dosage of 40 drops 3 times per day.
On
February, 26th., he has a new P.S.A. done which is in 7,4 ng/l, la
night urine has improved markedly, he keeps a good general state, he hasn’t
lost weight and good appetite.
On March, 7th.,
he is again evaluated by Oncology and Urology and is reported as clinically
cured.
All the
complementary exams are within normal parameters.
This is
summarizing my father’s situation, for which I am extremely grateful.
Kindly
yours,
Dra. Hilda
Smith.
From: valiacordero@hotmail.com
Sent:
Subject:
Patient’s Data
Name: Pablo
Surname:
Cordero
Date of
birth:
E-mail: valiacordero@hotmail.com
Contact: Daughter
Contact’s
name: Valia Cordero
City:
Country:
Telephone
number: (507)227-4382
Address: Calle 1a.
Perejil, Edificio Carmencita Apto. 5
Clinic
register: My father is 88 years old and
was until short time ago a healthy man who very seldom was ill, active and
seems to be much younger. He has ear troubles, frequent sickness or dizziness
and knee arthritis and in recent months trouble with urine retention. In
January of this year he was diagnosed prostate cancer.
He had
a bladder endoscopy done at the end of
March becoming positive and was indicated “Flutamide” one tablet 3 times per
day. The doctor has programmed a surgery to extirpate him the testicles this
Tuesday, 28th. but now that we have seen the web site about GREEN
SAP product we want to suspend this surgery and take this medicament because we
actually want him to have the opportunity to cure better than only palliative
measures.
Present
condition: He looses weight and is anaemic, he doesn’t have pelvic pains, occasionally
presents spasmodic bladder pains, he has a catheter to urinate.
How many
bottles does he need for about two months? How many drops and with which
frequency must he take them per day? What can you tell me about this new
treatment in this particular case? Please don’t be late to answer me and thank
you very much from now for your attention.
Valia
Cordero
Clinic
diagnosis: Bladder endoscopy: increased PSA – prostate with irregular in
consistence and badly defined right lobe. A needle biopsy was taken from both
lobes.
Anatomy
Pathology diagnosis: Pathologist inform: DIAGNOSIS:
A:
PROSTATE, RIGHT LOBE (BIOPSY):
-
Moderately
differentiated adenocarcinoma Gleason 3+4=7 which affects approximately 30% of
the sample, there is no peri-neural invasion.
-
There
is a high grade PIN focus.
-
Lympho
vascular permeation focus are observed.
B:
PROSTATE, LEFT LOBE (BIOPSY):
-
Moderately
differentiated adenocarcinoma Gleason 3+4=7 which affects approximately 20% of
the sample.
-
No
peri-neural or vascular invasion is observed.
This
biopsy’s results as I previously mentioned were done on March, 23rd.
A month later a centellogram was performed and bone metastasis were found but I
don’t know which grade.
Surgery: No
Kind of
surgery:
Chemotherapy:
Yes
Radiotherapy:
No
Dosage:
Tolerance
to medicament: Good
From: Valia
Cordero
Sent:
Subject:
Good news
Dear Dra.
García,
My greetinGREEN
SAP for you and the medical adviser staff from Drops.
The reason
of this mail is to inform you my father’s state of health, Pablo Cordero, who
began treating himself with Siqueiras Drops since last year. In this second
opportunity he took 30 bottles that we got through Dr. Freddy Henríquez and at
the present moment we are undergoing new dealinGREEN SAP with the Beneficence
Lottery Director, institution which is helping us economically to buy the
drops.
My father
underwent surgery on February, 11th., due to an intestinal occlusion
caused by the adherences of an old appendicitis surgery. He was very sick and
stayed hospitalised for 36 days, also due to a pneumonia because of the
infection with a hospital bacteria but
he is recovering satisfactorily.
Within this
urgency he was done a rectal exam and a CAT. In the rectal exam they found an
increased in size but soft prostate, the doctor mentioned that soft as a bubble
and not rocky. He didn’t show pain to the tact. The computerized tomography
showed a somewhat big prostate. The surgeon that attended my father informed us
that in the surgery area the intestines were free of cancer which was what they
feared. As I mentioned before, they only found part of the intestine (thin)
necrosed by the adherences.
Yesterday
we took my father to an Oncologist-Urologist physician who didn’t know about
his case and he actually found that my father had the prostate with a size of a
plump. He also found that the prostate was of a soft consistence as rubber and
had a small protuberance also soft. He was surprised that he had previously
been diagnosed with an advanced prostate cancer. Of course we also had given
him the biopsy laboratory result which verified that diagnosis. He told us that
if it weren’t for the biopsy he wouldn’t have believed it was the same patient
we were talking about.
Dr.
Monterrey, to whom we showed a GREEN SAP drops’ bottle, concluded that this
medicament that was the only thing he had taken, must have improved him from
the cancer. Nevertheless, he ordered several laboratory exams and X rays. He
told us that he would have liked to examined him at first so as he by himself
could have detected the change in his
improvement. He recommended us to go on giving him the drops. He was also
interested, not only in his prostate state but also in his general appearance
as he looks and feels like being fine although his recent disease of intestinal
occlusion. I left him a diskette record of the drops web site.
We are all
very happy and encouraged by the perspective that my father is cured or being
cured of the cancer and that we could recommend others this treatment.
We hope to
continue with the drops if God lets us and that my father uses this given time
to go on acquiring his Creator knowledge and establishes a precious friendship
relation with Him as God’s purpose by giving life’s gift to us is that we
search him and get to really know him.
I say
good-by to you,
Valia Cordero
From: Victor manuel
tabares Trujillo
Sent:
Subject:
Case wilms tumour recidivism
Appreciated
doctors,
Kind
greetinGREEN SAP.
My name is Victor Manuel Tabares Trujillo, father
of María Alejandra Tabares the girl who uncle Luis Gerardo Tabares refers to
who has already had communicated with you, and he informed to me about the
medicaments you are promoting for oncology treatments, interested in what you
offer and with the spirit of giving a better life quality to my daughter during
this process apart from finding other alternatives for solving this problem I
would like to present you the girl’s case so as you can advise me in the case.
María
Alejandra is 4 years old, last February, 12th., 2002 was detected a
big mass in the left abdominal flank, she had radiological analyses done such
as abdominal ultrasonography and after that a scan, where it was confirmed the
presence of a big mass in left kidney with the possibility of being a Wilms
Tumour, reason why an urgent surgery was programmed. Next Tuesday February, 19th.,
2002, it was performed an extirpation surgery of the left kidney with a Wilms
Tumour of 750 g. of weight which was sent to pathology for its analysis showing
the following result:
Surgical
pathology inform:
Microscopic
description: In the
histological cuts a malignant tumour lesion is identified, formed by a
blastomatose component, a epithelial one forming tubular structures and a
fusiform mesenquimal one. No anaplasic characteristic are observed. The tumour
compromises the kidney capsule but doesn’t perforate it. In the non tumour
kidney parenchyma there is tubular atrophy. No compromise of the kidney vein or
artery is observed, neither of the urether.
Diagnosis: Nefrectomy of left kidney
Tri-phase
Wilms Tumour with favourable histology
Kidney
capsule compromise without perforating it
Vascular
and urethral borders of extirpation free from tumour
According
to the results obtained from pathology it was determined the CHEMOTHERAPY
treatment with a protocol of 18 weeks with VINCRISTINE 0,05 mg/kg/d treatment
followed until week 10, ACTINOMICINE D 0,045 mg/kg/d every three weeks until
week 18. Such treatment started on February 22nd., 2002 and ended on
June 22nd., 2002.
During the
CHEMOTHERAPY treatment control exams were performed such as thorax
radiographies, hemogrames, creatinine, etc. obtaining very satisfactory
results, which indicated a very good surgery and chemotherapy result.
Last
October, 25th. a new abdominal control scan was done, and there were
obtained the following results:
Multiple
cuts in axial plan and with helicoidal technique were performed in the abdomen,
from lung basis to the pubis sinfisis, in simple phase and with 8 mm. Thickness
cuts. The study was asked without contrast medias.
FINDINGREEN
SAP:
Left nefrectomy changes are identified. The left kidney fosse is empty
and the tumour observed in the left kidney was completely extirpated. The
kidney fosse is occupied by thin intestine asas. Although it is difficult to
evaluate the retro-peritoneum without contrast, in the present cuts there is no
evidence of tumour recidivism. It catches the eye towards the left supra-kidney
gland, an hypodense image, of low density, which could represent residual
tumour or else an adrenal gland lesion. There is no pleural leakage or nodular
images.
What can be observed of the liver is of normal characteristics, with no
evidence of metastasic disease. There is no evidence of the gall via, intra or
extra liver. Coledoco and gall bladder normal. Spleen, pancreas, right
supra-kidney gland and right kidney without alterations. There is no evidence
of masses or retro-crural or retro-peritoneal adenomegalies. Cava vein and
aorta normal. No collections or ascitis liquid are observed. In the pelvis,
bladder, rectum and annexes are identified and normal. There are no pelvic
adenomegalies.
RADIOLOGIC CONCLUSIONS
-
NEFRECTOMY
WITH COMPLETE EXTIRPATION OF THE NEOPLASY OBSERVED IN THE PREVIOUS STUDY (
-
HYPODENSE
LESION IN LEFT SUPRA-KIDNEY GLAND, RESIDUAL TUMOUR OR METASTASIC DISEASE TO
CONSIDER.
-
THERE
IS NO EVIDENCE OF METASTASIC DISEASE IN ANOTHER PLACE OF THE ABDOMEN.
Due to this exam results it was determined a new laparotomy to determine
the finding with precision.
Last November, 7th., 2002 the surgery was done finding a new
tumour in the left supra-kidney gland of not very good aspect for the doctors
who participated in the surgery, it presented a necrosed part adhered to the
supra-kidney gland so they extirpated it completely, and the tumour was sent
again to pathology for its evaluation.
The pathologic evaluation showed the following result:
SURGICAL PATHOLOGY INFORM
SAMPLE
Left supra-kidney gland
MACROSCOPIC DESCRIPTION
It is received the product of extirpation of supra-kidney gland which
weighs 16 grms. And measures 5,5x3,8x1,2 cms. Supra-kidney gland can be
recognized and in the peripheries there is an hemorrhagic, lobated, partially
cystic nodule which measures 1,8x1,6x1,6 cms., which is partially opened, in
the same container and separately several brownish coloured tissue fragments
come, friable consistence which weigh 1 grm. Representative cuts are processed.
MICROSCOPIC DESCRIPTION.
In the histological cuts supra-kidney gland is identified which presents
in its capsule and fat that surrounds it primitive tumour lesion, formed by an
area of blastomatose aspect and others with tubular structures. THE TUMOUR HAS
QUITE A MITOTIC ACTIVITY. The material that comes separately corresponds to
tumour fragments partially necrotic, which surround striate muscle.
DIAGNOSIS
Left supra-kidney gland SUPRA-KIDNECTOMY
WILMS TUMOUR RECIDIVISM
The post-surgery recovery is very satisfactory, the girl is in excellent
state of health spiritually and nutritionally, she weighs 16 kGREEN SAP, as it
can be observed the tumour was focused with no evidence of metastasis in
another place.
Due to the results obtained from pathology it was determined a new
chemotherapy treatment adopting a more aggressive protocol of 24 weeks as it is
shown as follows.
CHEMOTHERAPY PROTOCOL FOR WILMS
TUMOUR STAGES II TO IV WITH DIFUSE ANAPLASY
Weeks
AAA
x
BBB
CCC
DDD
EEE
x
A = Doxorubicine
B= Ciclofosfamide
C= Etoposide
D= Vincristine
E= Vincristine
This
chemotherapy treatment will be reinforced with radiotherapy in the middle of
the process.
Last
Saturday, November 23rd. the chemotherapy was started as the
protocol determined.
I want to
know the product you offer and in which way it can help the girl in her
recovery and minimize the collateral effects of the treatment.
For the
attention you pay to these inquiries we will be infinitely grateful and with
the conviction that God will go on blessing you.
Kindly
yours,
VICTOR
MANUEL TABARES
LUZ MARINA MURIEL
(MOTHER)
MARIA ALEJANDRA TABARES
MURIEL (SICK BABY)
Santiago de Cali,
Colombia
From:
victor manuel tabares Trujillo
Sent:
Friday, February 14th., 2003,
Appreciated
doctors,
I would
like to thank you from my heart for having paid attention to my daughter’s
case, which has had a successful evolution during all this process she is going
through.
I tell you
that my girl is in a state of health that I would describe as enviable, after a
whole intense chemotherapy treatment the girls is in excellent spiritual and
nutritional state (from the beginning of the treatment she has put on 2 kGREEN
SAP.) and I wish to clear out that apart from the chemotherapy medicaments the
girls only was treated with the GREEN SAP Drops and with the Wilms Tumour
specific medicament that Dr. Medina sent us.
The results
obtained are excellent, thanks to God and to you, reason why we want to share
with you the evolution of the treatment we are following until now, so I attach
the Clinic record diary of the girl.
The girl’s
physician Dr. Fabio Dario Pereira is very interested in communicate with you to
share your experiences with the medicament and authorized me to give you his
e-mail address, so that you can have a direct contact and beneficiate more
children who are suffering from this disease, the e-mail is fpereira@andinet.com, God let you
contact.
I again
want to thank you for all, and wish you that God blesses you and the labour you
develop in the treatment of this disease.
Yours,
From: victor manuel tabares Trujillo
Sent:
Appreciated
doctors,
Kinds
greetinGREEN SAP.
Following
your solicitation, I am next sending you all the Clinic Record Diary of my
daughter from the very moment in which the problem was detected.
María
Alejandra is 4 years old, last February, 12th., 2002 was detected a
big mass in the left abdominal flank, she had radiological analyses done such
as abdominal ultrasonography and after that a scan, where it was confirmed the
presence of a big mass in left kidney with the possibility of being a Wilms
Tumour, reason why an urgent surgery was programmed. Next Tuesday February, 19th.,
2002, it was performed an extirpation surgery of the left kidney with a Wilms
Tumour of 750 g. of weight which was sent to pathology for its analysis showing
the following result:
Surgical
pathology inform:
Microscopic
description: In the
histological cuts a malignant tumour lesion is identified, formed by a
blastomatose component, a epithelial one forming tubular structures and a
fusiform mesenquimal one. No anaplasic characteristic are observed. The tumour
compromises the kidney capsule but doesn’t perforate it. In the non tumour
kidney parenchyma there is tubular atrophy. No compromise of the kidney vein or
artery is observed, neither of the urether.
Diagnosis: Nefrectomy of left kidney
Tri-phase
Wilms Tumour with favourable histology
Kidney
capsule compromise without perforating it
Vascular
and urethral borders of extirpation free from tumour
According
to the results obtained from pathology it was determined the CHEMOTHERAPY
treatment with a protocol of 18 weeks with VINCRISTINE 0,05 mg/kg/d treatment
followed until week 10, ACTINOMICINE D 0,045 mg/kg/d every three weeks until
week 18. Such treatment started on February 22nd., 2002 and ended on
June 22nd., 2002.
During the
CHEMOTHERAPY treatment control exams were performed such as thorax
radiographies, hemogrames, creatinine, etc. obtaining very satisfactory
results, which indicated a very good surgery and chemotherapy result.
Last
October, 25th. a new abdominal control scan was done, and there were
obtained the following results:
Multiple
cuts in axial plan and with helicoidal technique were performed in the abdomen,
from lung basis to the pubis sinfisis, in simple phase and with 8 mm. Thickness
cuts. The study was asked without contrast medias.
FINDINGREEN
SAP:
Left nefrectomy changes are identified. The left kidney fosse is empty
and the tumour observed in the left kidney was completely extirpated. The
kidney fosse is occupied by thin intestine asas. Although it is difficult to
evaluate the retro-peritoneum without contrast, in the present cuts there is no
evidence of tumour recidivism. It catches the eye towards the left supra-kidney
gland, an hypodense image, of low density, which could represent residual
tumour or else an adrenal gland lesion. There is no pleural leakage or nodular
images.
What can be observed of the liver is of normal characteristics, with no
evidence of metastasic disease. There is no evidence of the gall via, intra or
extra liver. Coledoco and gall bladder normal. Spleen, pancreas, right supra-kidney
gland and right kidney without alterations. There is no evidence of masses or
retro-crural or retro-peritoneal adenomegalies. Cava vein and aorta normal. No
collections or ascitis liquid are observed. In the pelvis, bladder, rectum and
annexes are identified and normal. There are no pelvic adenomegalies.
RADIOLOGIC CONCLUSIONS
-
NEFRECTOMY
WITH COMPLETE EXTIRPATION OF THE NEOPLASY OBSERVED IN THE PREVIOUS STUDY (
-
HYPODENSE
LESION IN LEFT SUPRA-KIDNEY GLAND, RESIDUAL TUMOUR OR METASTASIC DISEASE TO
CONSIDER.
-
THERE
IS NO EVIDENCE OF METASTASIC DISEASE IN ANOTHER PLACE OF THE ABDOMEN.
Due to this exam results it was determined a new laparotomy to determine
the finding with precision.
Last November, 7th., 2002 the surgery was done finding a new
tumour in the left supra-kidney gland of not very good aspect for the doctors
who participated in the surgery, it presented a necrosed part adhered to the
supra-kidney gland so they extirpated it completely, and the tumour was sent
again to pathology for its evaluation.
The pathologic evaluation showed the following result:
SURGICAL PATHOLOGY INFORM
SAMPLE
Left supra-kidney gland
MACROSCOPIC DESCRIPTION
It is received the product of extirpation of supra-kidney gland which
weighs 16 grms. And measures 5,5x3,8x1,2 cms. Supra-kidney gland can be
recognized and in the peripheries there is an hemorrhagic, lobated, partially
cystic nodule which measures 1,8x1,6x1,6 cms., which is partially opened, in
the same container and separately several brownish coloured tissue fragments
come, friable consistence which weigh 1 grm. Representative cuts are processed.
MICROSCOPIC DESCRIPTION.
In the histological cuts supra-kidney gland is identified which presents
in its capsule and fat that surrounds it primitive tumour lesion, formed by an
area of blastomatose aspect and others with tubular structures. THE TUMOUR HAS
QUITE A MITOTIC ACTIVITY. The material that comes separately corresponds to
tumour fragments partially necrotic, which surround striate muscle.
DIAGNOSIS
Left supra-kidney gland SUPRA-KIDNECTOMY
WILMS TUMOUR RECIDIVISM
The post-surgery recovery is very satisfactory, the girl is in excellent
state of health spiritually and nutritionally, she weighs 16 kGREEN SAP, as it
can be observed the tumour was focused with no evidence of metastasis in
another place.
Due to the results obtained from pathology it was determined a new
chemotherapy treatment adopting a more aggressive protocol of 24 weeks as it is
shown as follows.
CHEMOTHERAPY PROTOCOL FOR WILMS TUMOUR
STAGES II TO IV WITH DIFUSE ANAPLASY
Weeks
AAA
x
BBB
CCC
DDD
EEE
x
A = Doxorubicine
B= Ciclofosfamide
C= Etoposide
D= Vincristine
E= Vincristine
This
chemotherapy treatment will be reinforced with radiotherapy in the middle of
the process.
Last
Saturday, November 23rd. the chemotherapy was started as the
protocol determined.
Maria Alejandra
Tabares T.
*
November 7th., 2002 - Left supra-kidnectomy.
*
November 23rd., 2002 - CHEMOTHERAPY (Adriblastine-Razoxane-Ondansetron-Dexametasone),
she presented muscle pains, in the chest, general sickness, she threw out three
times in the breakfast of November 24th.,
25th. and 26th.
*
November 29th., 2002 - CHEMOTHERAPY (Vincristine 1mg.)
presented pain in chest, teeth, knees, she was treated with Acetaminofen and
Tramadol in order to reduce it, which persisted for four days she consulted the
oncologist and the Vincristine dose was reduced to 0,7 mg.
*December
7th., 2002 - Ambulatory SURGERY for installation of sub-clavial
central catheter, the procedure lasted an hour.
*December
8th., 2002
- Treatment with HOMEOPATHIC medicament GREEN
SAP DROPS is initiated. 5 drops half an hour before the meals and pepitas for
Wilms Tumour.
*December
11th., 2002 - HOSPITALISATION for Intense
Chemotherapy (Ciclofosfamide, Etoposide, Ondansetron, Dexametasone,
Hidratation), goes on with Homeopathic treatment.
*December
12th., 2002 - Hospitalised (Ciclofosfamide,
Etoposide, Ondansetron, Vincristine, Dexametasone, Hidratation), she presented
sickness due to previous day’s chemotherapy, irritable, short appetite, threw
out 3 times, started to loose hair, she goes on with Homeopathic treatment.
*December
13th., 2002 -
Hospitalised (Ciclofosfamide, Etoposide, Ondansetron, Dexametasone,
Hidratation), presents good mood, good appetite, without sickness, she goes on
with homeopathic treatment.
*December
14th., 2002 - Hospitalised (Etoposide,
Ondansetron, Dexametasone, Hidratation), very good mood, good appetite, without
sickness, she spent a very good day, she goes on with Homeopathic treatment.
*December
15th., 2002 - Hospitalised (Etoposide,
Ondansetron, Dexametasone, Hidratation), she spent a very good day, visit of
the oncologist and she is on release.
*December
19th., 2002 - Hemograme, Hemoglobine (10,3), Platelets
recount (360.000), weight increase from 15 kGREEN SAP. To 16 kGREEN SAP., very
good appetite, good general state.
*
December 21st., 2002 - CHEMOTHERAPY (Vincristine 0,7
mg.), without collateral effects, she goes on with Homeopathic treatment.
*December
28th., 2002 - CHEMOTHERAPY (Vincristine 0,7
mg.), without collateral effects, the endo-venous medicament is placed in right
hand, she goes on with Homeopathic treatment.
*December
29th. and 30th., 2002 - She presented possible knee pain
which is not confirmed, as it could be spoiling.
*January
4th., 2003 - CHEMOTHERAPY (Adriablastine-
Razoxane-Ondansetron-Dexametasone-Vincristine 0,7 mg.). She didn’t present
neither collateral effects nor complications, chemo placed in right hand’s
vein.
*January
11th., 2003 - CHEMOTHERAPY (Vincristine 0,7 mg.),
she goes on with Homeopathic treatment, placed in left hand, without collateral
effects.
*
January 20th., 2003 - HOSPITALISATION for Intense
Chemotherapy (Ciclofosfamide, Etoposide, Vincristine, Ondansetron,
Dexametasone, Hidratation), goes on with Homeopathic treatment. She didn’t
present collateral effects. Hemograme with platelet recount. Good result HGB
9,73 g/dl, PPLT 342 K/ul.
*January
21st., 2003 - Hospitalised (Ciclofosfamide,
Etoposide, Ondansetron, Dexametasone, Hidratation), she goes on with
homeopathic treatment. She was a little irritable, good appetite.
*January
22nd., 2003 - Hospitalised (Ciclofosfamide,
Etoposide, Ondansetron, Dexametasone, Hidratation), she goes on with
homeopathic treatment. Without collateral effects, good mood, good appetite,
irritability due to confinement not the medicaments.
*January
23rd., 2003 - Hospitalised
(Etoposide, Ondansetron, Dexametasone, Hidratation), she goes on with homeopathic
treatment. Good mood, good appetite.
*January
24th., 2003 - Hospitalised (Etoposide,
Ondansetron, Dexametasone, Hidratation), she goes on with homeopathic
treatment.
*
February 1st., 2003 - CHEMOTHERAPY (Vincristine 0,7
mg.), she goes on with Homeopathic treatment. Hemograme post-hospitalisation
HGB 10.30 g/dl, PLT 324 K/ul. Without collateral effects. It was only detected
in the girl some difficulty to talk, words stick to her, it seems as if it is
an effect of the VINCRISTINE.
*
February 8th., 2003 - CHEMOTHERAPY (Vincristine 0,7
mg.), she goes on with Homeopathic treatment. Without collateral effects, her
weight was checked observing an increase of almost two kilograms since her last
control, before the December’s hospitalisation.
*February
15th., 2003 - CHEMOTHERAPY (Adriablastine-
Razoxane-Ondansetron-Dexametasone-Vincristine 0,7 mg- Hidratation). She goes on
with Homeopathic treatment, without collateral effects.
*February 24th., 2003 - CHEMOTHERAPY (Etoposide, Ciclofosfamide,
Ondansetron, Dexametasone, Hidratation). She goes on with Homeopathic
treatment, without collateral effects.
*February
25th., 2003 - CHEMOTHERAPY (Etoposide,
Ciclofosfamide, Ondansetron, Dexametasone, Hidratation). She presented some
sickness with vomit and discourage. She goes on with Homeopathic treatment.
*February
26th., 2003 - CHEMOTHERAPY (Etoposide,
Ciclofosfamide, Ondansetron, Dexametasone, Hidratation). Collateral effects
disappear, good mood, good appetite, she goes on with Homeopathic treatment.
*February
27th., 2003 - CHEMOTHERAPY (Etoposide,
Ondansetron, Dexametasone, Hidratation). Without collateral effects, good mood,
good appetite, she goes on with Homeopathic treatment.
*February
28th., 2003 - CHEMOTHERAPY (Etoposide,
Ondansetron, Dexametasone,
GREEN SAP medical adviser team makes the
following hygienic-dietetic recommendations addressed to the patients, applying
them obviously to each pathology, state of health and nutritional state of each
patient.
What follows is an hygienic-dietetic
guide-line for patients with intestinal fuction conserved, without any other
complication, as they need other recommendations.
GUIDING DIET
Breakfast and tea: Each time light tea with
two spoonful of sugar. Two cookies or 10 buiscuits. Two thin slices of fatless
cheese.
Lunch and dinner: Each time chicken breast
without skin or fatless red meat filet, a small dish of common white rice, or
corn floor. Two grated or baked apples, peeled.
Intakes between foods: Two slices of fatless
ham or two cookies or its equivalent. Three baked meringues. If you feel hungry
you can add a portion of gelly.
Mineral water without gas used separated from
the food (though you can have lunch or dinner with a small glass).
ESOPHAGUS CANCER
Fractioned diet, soft (creams, gellies,
ice-creams, mashed food, blended).
Small quantity and frequent intake (6 times
per day).
Chew well, eat slowly.
Drink water with food.
Elevate the upper and back part of the bed
while resting so as to avoid stomach-esophagic reflux.
Avoid tobacco-stress, hot liquids (tea, coffe,
mate).
STOMACH CANCER
Frequent food, small quantity (creams,
gellies, ice-creams, white meat whitout skin, garlic, up to 80 grammes of non
smoked red meat).
Avoid stimulants (caffeine, tobacco, alcohol).
Drink liquids between food, not during them
different to esophagus.
Eat slowly, trying the diet to be soft.
LIVER-GALL AND PANCREATIC CANCER
Inform the patient that the gall increase can
produce diarrheas.
For this reason they must be excluded or
strictly reduced at the beginning and reincorporated in times to be defined due
to evolution the potent stimulating motility and/or secretion factors such as
fat, lactose, big volumes, insoluble fibre, cold liquids, hyper-osmolar
solutions, (mono and di-sacarid excess). Also exclude at the beginning coffe,
mate, and other strong infusions (alcohol, spicy seasoning, acid food).
Fats are restricted up to 20% of the total
calories or less than 20% with steatorrea or high caloric value. Lactose is
discarded and afterwards is reincorporated diluted following situation and
previous routine.
The intake of food must be fractioned in 6 or
more intakes of small amount, it is reduced the total quantity of fibre,
preferring pectine; they are modified by cooking and mechanic methods (smash,
blend, grate). Sacarose’s use must be controlled and irritants and cold
preparations are contraindicated.
Plenty of water must be consumed during the
day, avoid its use during the food, allow the loss of gas and don’t consume it
cold, add salt in normal quantities. All food will be fatless. The allowed food
will be amplifying, incorporating only one each time and observing if it makes
any inadequated effect. You will take into account the number and
characteristic of depositions to help to decide if the regime can be amplified.
All vegetables will be used without skini and seed, and prepared in a way that
their fibre may be “softened”. Control sugars and sweets.
ANAL CANCER
Avoid constipation.
Increased fibre, it is advised to add to the
normal intake (10 grammes-1000 kcal.) an extra amount of up to 20 grammes. This
intake is achieved only by using supplements or additioned food, less
quantities can improve the situation if the mean a sensible increase in
relation to the previous intake. Anyway the increase is performed gradually to
guarantee the intestinal adaptation, it is promoted the inclusion of insoluble
fibre to increase the fecal mass moreover the soluble fibre also improves in
the same way as it is used by the bacterian flora.
Increased liquids, two to three litres per day
added to what usually is consumed in the natural composition of the main food.
It can be chosen water of fruit juices, eventually mate or another infusions.
It is preferred sugarless, cold temperature, to stimulate peristaltism, and
without gas to avoid distension for excessive use.
Natural lubricants, oil and honey promote the
fecal mass to slip, if the nutritional state is normal, it is advised to
increase the total fat up to 30% of the caloric value and include honey as part
of the simple sugars allowed.
Probiotic addinGREEN SAP, for replacement of
the bacterian flora, yogurs are indicated preferably bio-yogur resistant to the
stomach ph.
Increase the organic acid, contained in the
majority of fruits and vegetables.
Food distribution, it is advised 4 basic foods
and 2 minor ones, promoting the adding of a minor food in fast, which
stimulates the stomach-duoden-yeyuno-colonic reflex. Choose a preparation of
maximum stimulation such as cold fruit juices adding honey or boiled or natural
fruit.
Avoid certain foods and beverages which have
gas and their effect is to distend theh abdomen and produce flatulency.
Chew correctly the aliments as well as swallow
well.
The intakes must be received in fixed time
schedules, feed slowly.
It is recommended to take skinless chicken,
baked fish, garlic, minimum red meat.
Avoid food which produce fermentation such as
legumes, vegetables in excess, etc.
Some medicaments’ absorption can be altered.
Avoid excess of weight.
In right colostomies, or transverse nearby
duoden, avoid raw or pasty vegetables, whole bread, stimulant beverages.
Some people tolerate badly milk, or fruit
juices.
Preferred food: water without gas, rice,
vermicelli, grout, fatless ham, fresh cheese without fermentation, peeled
fruit. Fatless milk and yoghourts. Green cooked legumes.
Avoid stimulant gas beverages, cereals,
sausages, pate, fat cheese (goat’s), dry fruits and laxants (altogether). Plain
milk, legumes rich in fibre.
BRONCHO-LUNG CANCER
It is recommended to drink plenty of liquid
without gas (at least 2 litres), white meat (chicken, fatless fish), up to 80
grammes of red meat.
Eat fruit, cooked vegetables and tubercules as
wanted.
If it is possible, intake of garlic.
Two spoonful of honey per day.
Don’t take alcoholic drinks.
Don’t eat fried food.
Try to perfom respiratory exercises to improve
blood oxygenation.
BREAST CANCER
Similar diet to normal, or healthy.
As a recommendation, minimum intake of red
meat on the frying pan with the less quantity of oil as possible.
EgGREEN SAP intake, preferably cooked, not
fried.
Consume at least one litre of fatless milk per
day.
Drink at least two litres of water without gas
per day.
Eat raw fresh fruit, vegetables, and
tubercules as wanted.
CENTRAL NERVOUS SYSTEM CANCER
It is recommended to intake liquids without
gas.
Food: cooked vegetables, fresh fruit, gellies,
iced creams, if there is good swallowing. White fatless meat (chicken, fish)
250 grammes per intake. Minimum of red meat, preferably cooked, one 150 grammes
portion per week. Eat garlic following tolerance. Don’t use very refined sugar
as edulcorant.
Saltless diet. Season food with lemmon.
Cereals at least two portions per day.
KIDNEY, BLADDER AND PROSTATE CANCER
Plenty consumption of liquids (3 litres per
day).
Eliminate alcohol, coffe, tea and other
irritants.
Fresh fruit and vegetables as wanted.
At least 125 grammes cereals per day.
Eat garlic if possible.
White fatless meat, red meat up to 80 grammes.
BIBLIOGRAFIA:
(1) De
Oliveira SQ, Dal-Pizzol F, Gosmann G, Guillaume D, Moreira JC, Schenkel
EP.
Antioxidant activity of Baccharis articulate extracts: isolation of a
new compound with antioxidant
activity. Free Radic Res. 2003 May;37(5):555-9.
(2) Zanon SM, Ceriatti FS, Rovera M, Sabini LJ, Ramos
BA. Search for antiviral activity of certain medicinal plants from
(3) Gamberini M., Skorupa L.A., Souccar C. & Lapa
A., Inhibition of gastric secretion by a water
extract from Baccharis triptera, Mart, Escola Paulista de Medicina Departamento de
Farmacologia INFAR,
(4)
Palacios et al. 1986.
(5) Mongelli E. et al., 1997
(6) Desmarchelier C.& Ciccia G., 1998.
(7) Soicke H. & Leng Peschlow E., 1987.
(8) Arisawa M. et al., 1985; Jarbis B. et al., 1988; Mongelli E. et al.,
1996.
(9) Simoes C. et al., 1986.
(10) Steiner
M, Priel I, Giat J, Levy J, Sharoni Y, Danilenko M. Carnosic acid
inhibits proliferation and augments differentiation of human leukemic cells
induced by 1,25-dihydroxyvitamin D3 and retinoic acid. Nutr Cancer.
2001;41(1-2):135-44.
(11) Offord EA, Mace K, Ruffieux C, Malnoe A, Pfeifer
AM. Rosemary components inhibit benzo[a]pyrene-induced genotoxicity in human
bronchial cells. Carcinogenesis.
1995 Sep;16(9):2057-62.
(12) Huang MT, Ho CT, Wang ZY, Ferraro T, Lou YR,
Stauber K, Ma W, Georgiadis C, Laskin JD, Conney AH. Inhibition of skin
tumorigenesis by rosemary and its
constituents carnosol and ursolic acid. Cancer Res. 1994 Feb 1;54(3):701-8.
(13) Galvez M, Martin-Cordero C, Lopez-Lazaro M, Cortes F, Ayuso MJ. Cytotoxic Effect of Plantago spp. on cancer cell lines.J
Ethnopharmacol. 2003 Oct;88(2-3):125-30.
(14) Hiang LC, Chiang W, Chang MY, Lin CC. In vitro
cytotoxic, antiviral and immunomodulatory effects of Plantago major and
Plantago asiatica. Am J Chin Med.
2003;31(2):225-34.
(15) Lin LT, Liu LT, Chiang LC, Lin CC. In vitro
anti-hepatoma activity of fifteen natural medicines from
(16) Ruffa MJ, Ferraro G, Wagner ML, Calcagno ML,
Campos RH, Cavallaro L. Cytotoxic effect of Argentine medicinal plant extracts on human hepatocellular carcinoma
cell line. J Ethnopharmacol. 2002 Mar;79(3):335-9.
(17) Gomez-Flores R, Calderon CL,
Scheibel LW, Tamez-Guerra P, Rodriguez-Padilla C, Tamez-Guerra R, Weber
RJ. Immunoenhancing properties of Plantago
major leaf extract. Phytother Res. 2000 Dec;14(8):617-22.
(18) Ikawati Z, Wahyuono S, Maeyama K. Screening
of several Indonesian medicinal plants for their inhibitory effect on histamine
release from RBL-2H3 cells. J Ethnopharmacol. 2001 May;75(2-3):249-56.
(19) Gomez-Flores R, Calderon CL, Scheibel LW, Tamez-Guerra P,
Rodriguez-Padilla C, Tamez-Guerra R, Weber RJ. Immunoenhancing
properties of Plantago major leaf extract. Phytother Res. 2000
Dec;14(8):617-22.
(20) Lithander A. Intracellular fluid of waybread
(Plantago major) as a prophylactic for mammary cancer in mice.Tumour Biol.
1992;13(3):138-41.
(21) Karpilovskaia ED, Gorban' GP,
(22) Chiang LC, Chiang W, Chang MY, Ng LT, Lin CC.
Antiviral activity of Plantago major extracts and related compounds in vitro.
Antiviral Res. 2002 Jul;55(1):53-62.
(23) Goodman y Gilman, 1991.
(24) Singletary K et al. 1991.
(25) Singletary K et al. 1997.
(26) Offord E. et al, 1997.
(27) Arizona, M. et al., 1985; Jorbis B. et al., 1988, Mangelli E. et al.,
1996.
(28) Cremaschi et al, J. Neuroimmunol, 2000, 110: 57.
(29) Suolinna
E. et al.: Quercetin, and artificial regulator of the high aerobic glycolisis
of tumour cells. J. National Cancer Inst. 53: 1515-19 (1974).
(30) Ip C. and Ganther H.:
Combination of blocking agents and suppressing agents in cancer prevention. Carcinogenesis.
12: 1193-96 (1991).